Nasal cavity disorder NOS

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VeDDRA Code: 1634

140 adverse event reports referencing this reaction

140
Total Reports
29
Deaths
2070.0%
Death Rate

Species Most Affected

Dog 105
Cat 27
Human 3
Horse 2
Other Birds 1
Cockatiel 1
Deer 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 10
Shepherd Dog - German 7
Crossbred Canine/dog 6
Dog (unknown) 6
Shih Tzu 5
Retriever - Golden 5
Terrier - Yorkshire 5
Chihuahua 5
Unknown 4

Associated Drugs

Milbemycin Oxime + Spinosad 12
Oclacitinib Maleate 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Spinosad 8
Selamectin 8
Maropitant Citrate 8
Cefovecin 7
Cyclosporine 7
Cyclosporine A 6
Prednisone 6
Fluralaner Chew Tablets 6
Trilostane 6
Afoxolaner 5
Enrofloxacin 4
Moxidectin 4
Anti-Il31 Mab Mcs Lot #1283563 4
Milbemycin Oxime + Praziquantel 4
Isoflurane 4
Florfenicol, Terbinafine, Betamethasone Acetate 4
Imidacloprid + Moxidectin 3

Data Summary

Metric Value
Total reports referencing reaction 140
Reports with fatal outcome 29
Case-fatality rate (reported events) 2070.0%
Species observed 7
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1634.

Nasal cavity disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 140 adverse event reports that reference Nasal cavity disorder NOS as a reaction term, including 29 reports with a death outcome — a 2070.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1634, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Nasal cavity disorder NOS appears most frequently in reports for Dog (105 reports), Cat (27 reports), Human (3 reports) — with Dog dominating at 105 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (17), Retriever - Labrador (10), Shepherd Dog - German (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Nasal cavity disorder NOS are Milbemycin Oxime + Spinosad (12 reports), Oclacitinib Maleate (12 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (10 reports), Spinosad (8 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial