Reaction profile

The FDA adverse-event record for nasal cavity disorder nos

140 FDA adverse-event reports reference nasal cavity disorder nos (VeDDRA 1634). See the species, breeds, and drugs most associated with it below.

140
reports citing this reaction
20.7%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
140
Total Reports
29
Deaths
20.7%
Death Rate

Species Most Affected

Dog 105
Cat 27
Human 3
Horse 2
Other Birds 1
Cockatiel 1
Deer 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 10
Shepherd Dog - German 7
Crossbred Canine/dog 6
Dog (unknown) 6
Shih Tzu 5
Retriever - Golden 5
Terrier - Yorkshire 5
Chihuahua 5
Unknown 4

Associated Drugs

Milbemycin Oxime + Spinosad 12
Oclacitinib Maleate 12
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Spinosad 8
Selamectin 8
Maropitant Citrate 8
Cefovecin 7
Cyclosporine 7
Cyclosporine A 6
Prednisone 6
Fluralaner Chew Tablets 6
Trilostane 6
Afoxolaner 5
Enrofloxacin 4
Moxidectin 4
Anti-Il31 Mab Mcs Lot #1283563 4
Milbemycin Oxime + Praziquantel 4
Isoflurane 4
Florfenicol, Terbinafine, Betamethasone Acetate 4
Imidacloprid + Moxidectin 3

Nasal cavity disorder NOS Reaction Insights

140 reports name Nasal cavity disorder NOS; 29 recorded a death outcome (20.7% of reported events, not a population-level mortality rate). VeDDRA code: 1634.

By species: Dog (105 reports), Cat (27 reports), Human (3 reports). By breed: Domestic Shorthair (17), Retriever - Labrador (10), Shepherd Dog - German (7).

Most co-reported drugs: Milbemycin Oxime + Spinosad (12 reports), Oclacitinib Maleate (12 reports), Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (10 reports), Spinosad (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.