Walking difficulty

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VeDDRA Code: 1902

4,623 adverse event reports referencing this reaction

4,623
Total Reports
981
Deaths
2120.0%
Death Rate

Species Most Affected

Dog 3,892
Cat 674
Horse 21
Cattle 20
Human 5
Goat 2
Sheep 2
Other Canids 1
Rabbit 1
Pig 1

Breeds Most Affected

Retriever - Labrador 426
Domestic Shorthair 407
Crossbred Canine/dog 256
Chihuahua 199
Shepherd Dog - German 172
Retriever - Golden 162
Dog (unknown) 146
Terrier - Yorkshire 126
Shih Tzu 124
Boxer (German Boxer) 102

Associated Drugs

Milbemycin Oxime + Spinosad 629
Bedinvetmab 439
Carprofen 357
Afoxolaner 337
Gabapentin 234
Maropitant Citrate 190
Pyrantel Pamoate;Sarolaner 185
Fluralaner 13.64% 12-Week Chew 184
Spinosad 179
Ivermectin + Pyrantel As Pamoate Salt 168
Sarolaner 165
Fluralaner Chew Tablets 163
Cefovecin 159
Moxidectin 143
Oclacitinib Maleate 142
Selamectin 136
Prednisone 135
Trilostane 119
Milbemycin Oxime + Praziquantel 103
Grapiprant 87

Data Summary

Metric Value
Total reports referencing reaction 4,623
Reports with fatal outcome 981
Case-fatality rate (reported events) 2120.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1902.

Walking difficulty Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 4,623 adverse event reports that reference Walking difficulty as a reaction term, including 981 reports with a death outcome — a 2120.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1902, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Walking difficulty appears most frequently in reports for Dog (3,892 reports), Cat (674 reports), Horse (21 reports) — with Dog dominating at 3,892 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (426), Domestic Shorthair (407), Crossbred Canine/dog (256). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Walking difficulty are Milbemycin Oxime + Spinosad (629 reports), Bedinvetmab (439 reports), Carprofen (357 reports), Afoxolaner (337 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 629 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial