Reaction profile

The FDA adverse-event record for inappropriate schedule of drug administration

1,075 FDA adverse-event reports reference inappropriate schedule of drug administration (VeDDRA 99832). See the species, breeds, and drugs most associated with it below.

1,075
reports citing this reaction
2.1%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
1,075
Total Reports
23
Deaths
2.1%
Death Rate

Species Most Affected

Dog 994
Cat 41
Horse 24
Cattle 11
Sheep 2
Pig 1
Goat 1
Mouse 1

Breeds Most Affected

Retriever - Labrador 84
Dog (unknown) 48
Terrier - Yorkshire 47
Crossbred Canine/dog 44
Shih Tzu 43
Chihuahua 40
Retriever - Golden 40
Shepherd Dog - German 38
Terrier - Bull - American Pit 30
Maltese 30

Associated Drugs

Oclacitinib Maleate 587
Anti-Il31 Mab Mcs Lot #1283563 137
Trilostane 106
Polysulfated Glycosaminoglycan 44
Melarsomine Dihydrochloride 34
Milbemycin Oxime + Spinosad 32
Prednisone 24
Ivermectin + Pyrantel As Pamoate Salt 23
Afoxolaner 21
Moxidectin 21
Fluralaner 13.64% 12-Week Chew 19
Gabapentin 18
Carprofen 16
Milbemycin Oxime + Praziquantel 16
Fluralaner Chew Tablets 14
Selamectin 13
Diphenhydramine Hcl 13
Spinosad 13
Cefpodoxime Proxetil 12
Cefovecin 11

Inappropriate schedule of drug administration Reaction Insights

1,075 reports name Inappropriate schedule of drug administration; 23 recorded a death outcome (2.1% of reported events, not a population-level mortality rate). VeDDRA code: 99832.

By species: Dog (994 reports), Cat (41 reports), Horse (24 reports). By breed: Retriever - Labrador (84), Dog (unknown) (48), Terrier - Yorkshire (47).

Most co-reported drugs: Oclacitinib Maleate (587 reports), Anti-Il31 Mab Mcs Lot #1283563 (137 reports), Trilostane (106 reports), Polysulfated Glycosaminoglycan (44 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.