Reaction profile

The FDA adverse-event record for impurity

52 FDA reports name impurity, a lower-volume reaction in the CVM extract (VeDDRA 93154). Plate stamps and neighbourhood peers follow.

#1717 of 2,481
by report volume (all reactions)
52
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Impurity has 52 reports now versus 52 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Impurity changes

FDA AER · VeDDRA plate

Code 93154 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-NARROW · BOOK-FULL

  • VOL-LOW 52 reports
  • DEATH-RARE 0.0%
  • MID-PACK #1717/2481
  • PHOTO-FINISH Decreased intra-ocula…
  • SPECIES-UNKNOWN Unknown · 51
  • DRUG-LEAD Moxidectin · 23
  • DESK-NARROW 2 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased intra-ocular pressure (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Impurity

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Decreased intra-ocula… · near52Hypersensitivity to p… · near52Impurity · this reaction52Injection site haemor… · near52Intestinal haemorrhage · near52Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Impurity

Impurity: low death-coded share in the FDA AER plate

Signature read: Impurity's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 52 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 52 reports (0.0% of named reports). Nearest volume peer: Decreased intra-ocular pressure (±0 reports). Lead species Unknown (51). Lead co-reported drug Moxidectin (23).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 51
Cat 1

Breeds Most Affected

Unknown 51
Cat (other) 1

Associated Drugs

Moxidectin 23
Propofol 9
Cefovecin 5
Oclacitinib Maleate 2
Imidacloprid + Moxidectin 2
Ivermectin 2
Oxytetracycline Anhydrous 1
Levothyroxine Sodium Powder 1
Sodium Hyaluronate 1
Maropitant Citrate 1
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 1
Ivermectin + Praziquantel 1
Clotrimazole + Gentamicin + Mometasone 1
Cloxacillin Benz Intramam Dc 1
Estradiol + Trenbolone 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Impurity, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Impurity (#1717 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →