Drunken gait

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VeDDRA Code: 1133

532 adverse event reports referencing this reaction

532
Total Reports
53
Deaths
1000.0%
Death Rate

Species Most Affected

Dog 430
Cat 94
Horse 4
Cattle 3
Turkey 1

Breeds Most Affected

Domestic Shorthair 60
Crossbred Canine/dog 41
Retriever - Labrador 40
Chihuahua 21
Shepherd Dog - German 19
Shih Tzu 17
Terrier - Yorkshire 14
Boxer (German Boxer) 12
Maltese 11
Retriever - Golden 11

Associated Drugs

Milbemycin Oxime + Spinosad 153
Spinosad 60
Afoxolaner 30
Fluralaner 13.64% 12-Week Chew 30
Ivermectin + Pyrantel As Pamoate Salt 26
Ivermectin 25
Fluralaner Chew Tablets 21
Milbemycin Oxime + Praziquantel 18
Fluralaner Spot-On Solution 17
Nitenpyram 16
Fluralaner/Moxidectin Spot-On 14
Gabapentin 13
Carprofen 12
Milbemycin/Lufenuron/Pzq Chew 11
Trilostane 10
Bedinvetmab 10
Selamectin 9
Lotilaner 8
Meloxicam 7
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 7

Data Summary

Metric Value
Total reports referencing reaction 532
Reports with fatal outcome 53
Case-fatality rate (reported events) 1000.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1133.

Drunken gait Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 532 adverse event reports that reference Drunken gait as a reaction term, including 53 reports with a death outcome — a 1000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1133, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Drunken gait appears most frequently in reports for Dog (430 reports), Cat (94 reports), Horse (4 reports) — with Dog dominating at 430 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (60), Crossbred Canine/dog (41), Retriever - Labrador (40). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Drunken gait are Milbemycin Oxime + Spinosad (153 reports), Spinosad (60 reports), Afoxolaner (30 reports), Fluralaner 13.64% 12-Week Chew (30 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 153 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial