Reaction profile

The FDA adverse-event record for drunken gait

532 FDA adverse-event reports reference drunken gait (VeDDRA 1133). See the species, breeds, and drugs most associated with it below.

532
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
532
Total Reports
53
Deaths
10.0%
Death Rate

Species Most Affected

Dog 430
Cat 94
Horse 4
Cattle 3
Turkey 1

Breeds Most Affected

Domestic Shorthair 60
Crossbred Canine/dog 41
Retriever - Labrador 40
Chihuahua 21
Shepherd Dog - German 19
Shih Tzu 17
Terrier - Yorkshire 14
Boxer (German Boxer) 12
Maltese 11
Retriever - Golden 11

Associated Drugs

Milbemycin Oxime + Spinosad 153
Spinosad 60
Afoxolaner 30
Fluralaner 13.64% 12-Week Chew 30
Ivermectin + Pyrantel As Pamoate Salt 26
Ivermectin 25
Fluralaner Chew Tablets 21
Milbemycin Oxime + Praziquantel 18
Fluralaner Spot-On Solution 17
Nitenpyram 16
Fluralaner/Moxidectin Spot-On 14
Gabapentin 13
Carprofen 12
Milbemycin/Lufenuron/Pzq Chew 11
Trilostane 10
Bedinvetmab 10
Selamectin 9
Lotilaner 8
Meloxicam 7
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 7

Drunken gait Reaction Insights

532 reports name Drunken gait; 53 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 1133.

By species: Dog (430 reports), Cat (94 reports), Horse (4 reports). By breed: Domestic Shorthair (60), Crossbred Canine/dog (41), Retriever - Labrador (40).

Most co-reported drugs: Milbemycin Oxime + Spinosad (153 reports), Spinosad (60 reports), Afoxolaner (30 reports), Fluralaner 13.64% 12-Week Chew (30 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.