Digestive tract stenosis and obstruction NOS

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VeDDRA Code: 310

93 adverse event reports referencing this reaction

93
Total Reports
25
Deaths
2690.0%
Death Rate

Species Most Affected

Dog 83
Cat 8
Horse 2

Breeds Most Affected

Retriever - Labrador 11
Terrier - West Highland White 7
Chihuahua 6
Retriever - Golden 6
Dachshund (unspecified) 4
Dog (unknown) 4
Boxer (German Boxer) 4
Beagle 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Cat (unknown) 2

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 22
Spinosad 7
Afoxolaner 7
Ivermectin, Pyrantel 6
Milbemycin Oxime + Spinosad 4
Meloxicam 4
Milbemycin Oxime + Praziquantel 4
Nitenpyram 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Buprenorphine 3
Pimobendan 3
Imidacloprid + Moxidectin 2
Firocoxib 227 Mg Chewable 2
Febantel + Praziquantel + Pyrantel Pamoate 2
Midazolam 2
Propofol 2
Maropitant Citrate 2
Milbemycin Oxime, Lufenuron 2
Prednisone 2
Firocoxib 2

Data Summary

Metric Value
Total reports referencing reaction 93
Reports with fatal outcome 25
Case-fatality rate (reported events) 2690.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 310.

Digestive tract stenosis and obstruction NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 93 adverse event reports that reference Digestive tract stenosis and obstruction NOS as a reaction term, including 25 reports with a death outcome — a 2690.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 310, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Digestive tract stenosis and obstruction NOS appears most frequently in reports for Dog (83 reports), Cat (8 reports), Horse (2 reports) — with Dog dominating at 83 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (11), Terrier - West Highland White (7), Chihuahua (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Digestive tract stenosis and obstruction NOS are Ivermectin + Pyrantel As Pamoate Salt (22 reports), Spinosad (7 reports), Afoxolaner (7 reports), Ivermectin, Pyrantel (6 reports), with Ivermectin + Pyrantel As Pamoate Salt appearing alongside this reaction in 22 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial