Reaction profile

The FDA adverse-event record for digestive tract stenosis and obstruction nos

93 FDA adverse-event reports reference digestive tract stenosis and obstruction nos (VeDDRA 310). See the species, breeds, and drugs most associated with it below.

93
reports citing this reaction
26.9%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel As Pamoate Salt
most-associated drug
Verify with FDA CVM →
93
Total Reports
25
Deaths
26.9%
Death Rate

Species Most Affected

Dog 83
Cat 8
Horse 2

Breeds Most Affected

Retriever - Labrador 11
Terrier - West Highland White 7
Chihuahua 6
Retriever - Golden 6
Dachshund (unspecified) 4
Dog (unknown) 4
Boxer (German Boxer) 4
Beagle 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Cat (unknown) 2

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 22
Spinosad 7
Afoxolaner 7
Ivermectin, Pyrantel 6
Milbemycin Oxime + Spinosad 4
Meloxicam 4
Milbemycin Oxime + Praziquantel 4
Nitenpyram 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Buprenorphine 3
Pimobendan 3
Imidacloprid + Moxidectin 2
Firocoxib 227 Mg Chewable 2
Febantel + Praziquantel + Pyrantel Pamoate 2
Midazolam 2
Propofol 2
Maropitant Citrate 2
Milbemycin Oxime, Lufenuron 2
Prednisone 2
Firocoxib 2

Digestive tract stenosis and obstruction NOS Reaction Insights

93 reports name Digestive tract stenosis and obstruction NOS; 25 recorded a death outcome (26.9% of reported events, not a population-level mortality rate). VeDDRA code: 310.

By species: Dog (83 reports), Cat (8 reports), Horse (2 reports). By breed: Retriever - Labrador (11), Terrier - West Highland White (7), Chihuahua (6).

Most co-reported drugs: Ivermectin + Pyrantel As Pamoate Salt (22 reports), Spinosad (7 reports), Afoxolaner (7 reports), Ivermectin, Pyrantel (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.