Reaction profile

The FDA adverse-event record for application site skin slough

10 FDA adverse-event reports reference application site skin slough (VeDDRA 3046). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
0.0%
death-coded share
Cat
most-affected species
Tigilanol Tiglate
most-associated drug
Verify with FDA CVM →
10
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Cat 6
Dog 3
Cattle 1

Breeds Most Affected

Domestic Mediumhair 3
Domestic Shorthair 2
Aberdeen Angus 1
Boxer (German Boxer) 1
Bulldog - French 1
Persian 1
Pit Bull 1

Associated Drugs

Tigilanol Tiglate 2
Prednisone 2
Diphenhydramine 2
Famotidine 2
Gabapentin 2
Neo-Poly-Bac Ointment 2
Selamectin;Sarolaner 2
Eprinomectin + Esafoxolaner + Praziquantel 1
Dinoprost Tromethamine 1
Cystorelin 1
Selamectin 1
Butorphanol Tartrate 1
Dexmedetomidine 1
Alfaxalone 1
Maropitant Citrate 1
Buprenorphine 1
Isoflurane 1
Acepromazine 1
Butorphanol 1
Oxygen 1

Application site skin slough Reaction Insights

10 reports name Application site skin slough; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 3046.

By species: Cat (6 reports), Dog (3 reports), Cattle (1 reports). By breed: Domestic Mediumhair (3), Domestic Shorthair (2), Aberdeen Angus (1).

Most co-reported drugs: Tigilanol Tiglate (2 reports), Prednisone (2 reports), Diphenhydramine (2 reports), Famotidine (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.