IGA Animal mortality greater than expected

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VeDDRA Code: 93102

69 adverse event reports referencing this reaction

69
Total Reports
69
Deaths
10000.0%
Death Rate

Species Most Affected

Fish 41
Chicken 26
Chinchilla 1
Pig 1

Breeds Most Affected

Atlantic Salmon (Salmo salar) 41
Unknown 27
Pig (other) 1

Associated Drugs

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) 35
Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. 16
Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal 11
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage 5
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The Alocus In The Eo-1A Lineage) 1
Deletion Of Exon 7 Of Cd163 Gene In Domestic Pigs 1

Data Summary

Metric Value
Total reports referencing reaction 69
Reports with fatal outcome 69
Case-fatality rate (reported events) 10000.0%
Species observed 4
Breeds observed 3
Drugs associated with reaction 6

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 93102.

IGA Animal mortality greater than expected Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 69 adverse event reports that reference IGA Animal mortality greater than expected as a reaction term, including 69 reports with a death outcome — a 10000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 93102, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

IGA Animal mortality greater than expected appears most frequently in reports for Fish (41 reports), Chicken (26 reports), Chinchilla (1 reports) — with Fish dominating at 41 entries. Within those species, the breeds most often named alongside this reaction are Atlantic Salmon (Salmo salar) (41), Unknown (27), Pig (other) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with IGA Animal mortality greater than expected are Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) (35 reports), Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. (16 reports), Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal (11 reports), Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage (5 reports), with Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) appearing alongside this reaction in 35 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial