Reaction profile

The FDA adverse-event record for iga animal mortality greater than expected

69 FDA adverse-event reports reference iga animal mortality greater than expected (VeDDRA 93102). See the species, breeds, and drugs most associated with it below.

69
reports citing this reaction
100.0%
death-coded share
Fish
most-affected species
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage)
most-associated drug
Verify with FDA CVM →
69
Total Reports
69
Deaths
100.0%
Death Rate

Species Most Affected

Fish 41
Chicken 26
Chinchilla 1
Pig 1

Breeds Most Affected

Atlantic Salmon (Salmo salar) 41
Unknown 27
Pig (other) 1

Associated Drugs

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) 35
Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. 16
Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal 11
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage 5
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The Alocus In The Eo-1A Lineage) 1
Deletion Of Exon 7 Of Cd163 Gene In Domestic Pigs 1

IGA Animal mortality greater than expected Reaction Insights

69 reports name IGA Animal mortality greater than expected; 69 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). VeDDRA code: 93102.

By species: Fish (41 reports), Chicken (26 reports), Chinchilla (1 reports). By breed: Atlantic Salmon (Salmo salar) (41), Unknown (27), Pig (other) (1).

Most co-reported drugs: Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) (35 reports), Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. (16 reports), Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal (11 reports), Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.