Reaction profile

The FDA adverse-event record for iga animal mortality greater than expected

Name: IGA Animal mortality greater than expected - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

72 FDA adverse-event reports reference iga animal mortality greater than expected (VeDDRA 93102). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1557 of 2,481
by report volume (all reactions): 72
reports citing this reaction: 100.0%
death-coded share: Fish
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. IGA Animal mortality greater than expected has 72 reports now versus 70 in that prior snapshot: 2 more (2.9%).

Report change: +2
Death-coded reports: +2
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to IGA Animal mortality greater than expected changes

FDA AER · VeDDRA plate

Code 93102 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-FISH · DRUG-LEAD · DESK-NARROW · BOOK-FULL

VOL-LOW 72 reports
DEATH-HOT 100.0%
MID-PACK #1557/2481
PHOTO-FINISH Ear flapping/twitching
SPECIES-FISH Fish · 41
DRUG-LEAD Atlantic Salmon T… · 35
DESK-NARROW 3 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Ear flapping/twitching (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around IGA Animal mortality greater than expected

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

FDA AER report volume · neighbourhood around IGA Animal mortality greater than expected

IGA Animal mortality greater than expected: high death-coded share in the FDA AER plate

Signature read: IGA Animal mortality greater than expected's 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 72 of 72 reports (100.0% of named reports). Nearest volume peer: Ear flapping/twitching (±0 reports). Lead species Fish (41). Lead co-reported drug Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) (35).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Fish 41

Chicken 27

Pig 3

Chinchilla 1

Breeds Most Affected

Atlantic Salmon (Salmo salar) 41

Unknown 28

Pig (other) 3

Associated Drugs

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) 35

Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal. 17

Sebelipase Alfa Strength Indicated Is For Final Drug Product And Is Not Administered To The Animal 11

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage 5

Deletion Of Exon 7 Of Cd163 Gene In Domestic Pigs 3

Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The Alocus In The Eo-1A Lineage) 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for IGA Animal mortality greater than expected, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (72 here).

Ear flapping/twitching 72 Elevated BUN 72 Embolism 72 Fatty liver 72

Similar death-coded share

Nearest other reactions by death-coded share (100.0% here), distinct from the volume row.

NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 100.0% PR-ADRENAL(S), LESION(S) 100.0% PR-LUNG(S), EDEMA 100.0% Found dead 99.8%

What to do with this reaction

Compare IGA Animal mortality greater than expected's report profile against similar reactions nationwide. See similar reactions
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for IGA Animal mortality greater than expected (#1557 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →