Reaction profile

The FDA adverse-event record for neoplasia nos

1,770 FDA reports name neoplasia nos, a high-volume reaction in the CVM extract (VeDDRA 1928). Plate stamps and neighbourhood peers follow.

#255 of 2,481
by report volume (all reactions)
1,770
reports citing this reaction
50.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neoplasia NOS has 1,770 reports now versus 1,755 in that prior snapshot: 15 more (0.9%).

Report change
+15
Death-coded reports
+3
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neoplasia NOS changes

FDA AER · VeDDRA plate

Code 1928 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,770 reports
  • DEATH-HOT 50.7%
  • UPPER-Q #255/2481
  • PHOTO-FINISH Sneezing
  • SPECIES-DOG Dog · 1,595
  • DRUG-LEAD Oclacitinib Malea… · 476
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Sneezing (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Neoplasia NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Alopecia · near1797Neoplasia NOS · this reaction1770Sneezing · near1770Distension of abdomen · near1754Crying · near1751Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Neoplasia NOS

Neoplasia NOS: high death-coded share in the FDA AER plate

Signature read: 898 death-coded reports is a heavy tail count for Neoplasia NOS in the CVM extract. Report volume is upper-third scale: 1,770 named reports in the openFDA extract. Death-coded share is upper-third: 898 of 1,770 reports (50.7% of named reports). Nearest volume peer: Sneezing (±0 reports). Lead species Dog (1,595). Lead co-reported drug Oclacitinib Maleate (476).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,595
Cat 161
Cattle 5
Horse 4
Human 3
Rabbit 1
Ferret 1

Breeds Most Affected

Dog (unknown) 289
Retriever - Labrador 175
Retriever - Golden 90
Crossbred Canine/dog 76
Boxer (German Boxer) 62
Domestic Shorthair 62
Shepherd Dog - German 60
Terrier - Bull - American Pit 54
Pit Bull 34
Beagle 33

Associated Drugs

Oclacitinib Maleate 476
Milbemycin Oxime + Spinosad 272
Ivermectin + Pyrantel As Pamoate Salt 169
Spinosad 75
Afoxolaner 74
Milbemycin Oxime + Praziquantel 69
Carprofen 63
Cyclosporine 60
Bedinvetmab 59
Trilostane 52
Anti-Il31 Mab Mcs Lot #1283563 44
Gabapentin 41
Cyclosporine A 37
Grapiprant 36
Maropitant Citrate 35
Prednisone 35
Fluralaner Chew Tablets 34
Imidacloprid + Moxidectin 31
Moxidectin 29
Milbemycin Oxime 29

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Neoplasia NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,770 here).

Similar death-coded share

Nearest other reactions by death-coded share (50.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neoplasia NOS (#255 of 2,481 by report volume); death-coded 50.7%. PlainBreed reaction plate · death-coded report count stamp 898 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →