Reaction profile

The FDA adverse-event record for vulvitis

70 FDA adverse-event reports reference vulvitis (VeDDRA 823). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1579 of 2,481
by report volume (all reactions)
70
reports citing this reaction
7.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vulvitis has 70 reports now versus 69 in that prior snapshot: 1 more (1.4%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vulvitis changes

FDA AER · VeDDRA plate

Code 823 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 70 reports
  • DEATH-PAR 7.1%
  • MID-PACK #1579/2481
  • PHOTO-FINISH Application site warm…
  • SPECIES-DOG Dog · 62
  • DRUG-LEAD Estriol · 17
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site warmth (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Vulvitis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site warm… · near70Digestive tract hyper… · near70Hyporeflexia · near70Musculoskeletal neopl… · near70Vulvitis · this reaction70Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vulvitis

Vulvitis: low death-coded share in the FDA AER plate

Signature read: 5 death-coded reports is a thin tail count for Vulvitis in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 5 of 70 reports (7.1% of named reports). Nearest volume peer: Application site warmth (±0 reports). Lead species Dog (62). Lead co-reported drug Estriol (17).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Estriol appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 62
Cattle 4
Cat 2
Pig 2

Breeds Most Affected

Crossbred Canine/dog 6
Shepherd Dog - German 4
Terrier - Yorkshire 4
Pit Bull 3
Retriever - Golden 3
Sheepdog - Shetland 2
Spitz - German Pomeranian 2
Dachshund (unspecified) 2
Aberdeen Angus 2
Boxer (German Boxer) 2

Associated Drugs

Estriol 17
Oclacitinib Maleate 5
Carprofen 4
Trilostane 4
Milbemycin Oxime + Spinosad 4
Imidacloprid + Moxidectin 3
Estriol Tablets 3
Glycosaminoglycan Polysulfate 2
Cefpodoxime Proxetil 2
Dinoprost Tromethamine 2
Spinosad 2
Altrenogest 2
Diphenhydramine 2
Sarolaner 2
Pyrantel Pamoate;Sarolaner 2
Prescription Diet (Unspecified) 2
Amoxicillin, Clavulanate 1
Dirlotapide 1
Cyclosporine 1
Monensin 1

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Vulvitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (7.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vulvitis (#1579 of 2,481 by report volume); death-coded 7.1%. PlainBreed reaction plate · death-coded report count stamp 5 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →