Reaction profile

The FDA adverse-event record for tenesmus

369 FDA reports name tenesmus, a high-volume reaction in the CVM extract (VeDDRA 273). Plate stamps and neighbourhood peers follow.

#776 of 2,481
by report volume (all reactions)
369
reports citing this reaction
13.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tenesmus has 369 reports now versus 368 in that prior snapshot: 1 more (0.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tenesmus changes

FDA AER · VeDDRA plate

Code 273 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 369 reports
  • DEATH-ELEV 13.8%
  • MID-PACK #776/2481
  • PHOTO-FINISH Blood and lymphatic s…
  • SPECIES-DOG Dog · 331
  • DRUG-LEAD Milbemycin Oxime… · 31
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Blood and lymphatic system disorder NOS (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Tenesmus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Blood and lymphatic s… · near369Tenesmus · this reaction369Abdominal cavity haem… · near368Jaw disorder · near368Lot # and/or Expirati… · near368Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tenesmus

What the FDA AER plate says about Tenesmus

Signature read: 51 death-coded reports is a heavy tail count for Tenesmus in the CVM extract. Report volume is upper-third scale: 369 named reports in the openFDA extract. 51 of 369 reports were death-coded (13.8% of named reports, not a population mortality rate). Nearest volume peer: Blood and lymphatic system disorder NOS (±0 reports). Lead species Dog (331). Lead co-reported drug Milbemycin Oxime + Spinosad (31).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 331
Cat 31
Cattle 5
Horse 2

Breeds Most Affected

Crossbred Canine/dog 32
Retriever - Labrador 27
Shepherd Dog - German 16
Retriever - Golden 15
Dachshund (unspecified) 15
Domestic Shorthair 13
Shih Tzu 10
Pit Bull 10
Chihuahua 9
Spaniel - Cocker American 9

Associated Drugs

Milbemycin Oxime + Spinosad 31
Carprofen 25
Ivermectin + Pyrantel As Pamoate Salt 20
Afoxolaner 18
Spinosad 15
Cyclosporine A 15
Cyclosporine 14
Meloxicam 13
Selamectin 12
Imidacloprid + Moxidectin 12
Fluralaner Chew Tablets 12
Maropitant Citrate 11
Moxidectin 10
Deracoxib 10
Tramadol 10
Milbemycin Oxime + Praziquantel 8
Lufenuron + Milbemycin Oxime 7
Cefovecin 7
Milbemycin Oxime, Lufenuron 7
Gabapentin 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Tenesmus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (13.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tenesmus (#776 of 2,481 by report volume); death-coded 13.8%. PlainBreed reaction plate · death-coded report count stamp 51 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →