Reaction profile

The FDA adverse-event record for polyuria

7,322 FDA adverse-event reports reference polyuria (VeDDRA 718). See the species, breeds, and drugs most associated with it below.

7,322
reports citing this reaction
9.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
7,322
Total Reports
716
Deaths
9.8%
Death Rate

Species Most Affected

Dog 6,517
Cat 692
Horse 105
Cattle 2
Human 2
Pig 1
Monkey 1
Goat 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 774
Crossbred Canine/dog 463
Domestic Shorthair 395
Retriever - Golden 268
Shepherd Dog - German 245
Boxer (German Boxer) 219
Dog (unknown) 187
Terrier - Yorkshire 163
Chihuahua 156
Shih Tzu 153

Associated Drugs

Bedinvetmab 1,370
Trilostane 1,101
Carprofen 662
Oclacitinib Maleate 590
Prednisone 431
Gabapentin 342
Milbemycin Oxime + Spinosad 276
Fluralaner Chew Tablets 247
Maropitant Citrate 239
Pyrantel Pamoate;Sarolaner 213
Desoxycorticosterone Pivalate 196
Bexagliflozin 184
Afoxolaner 175
Deracoxib 173
Meloxicam 168
Cyclosporine 158
Moxidectin 156
Grapiprant 152
Anti-Il31 Mab Mcs Lot #1283563 150
Lotilaner 144

Polyuria Reaction Insights

7,322 reports name Polyuria; 716 recorded a death outcome (9.8% of reported events, not a population-level mortality rate). VeDDRA code: 718.

By species: Dog (6,517 reports), Cat (692 reports), Horse (105 reports). By breed: Retriever - Labrador (774), Crossbred Canine/dog (463), Domestic Shorthair (395).

Most co-reported drugs: Bedinvetmab (1,370 reports), Trilostane (1,101 reports), Carprofen (662 reports), Oclacitinib Maleate (590 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.