Reaction profile

The FDA adverse-event record for not urinating

587 FDA reports name not urinating, a high-volume reaction in the CVM extract (VeDDRA 2520). Plate stamps and neighbourhood peers follow.

#581 of 2,481
by report volume (all reactions)
587
reports citing this reaction
23.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Not urinating has 587 reports now versus 563 in that prior snapshot: 24 more (4.3%).

Report change
+24
Death-coded reports
+6
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Not urinating changes

FDA AER · VeDDRA plate

Code 2520 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 587 reports
  • DEATH-HOT 23.2%
  • UPPER-Q #581/2481
  • PHOTO-FINISH Immediate pain upon i…
  • SPECIES-DOG Dog · 337
  • DRUG-LEAD Buprenorphine · 106
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Immediate pain upon injection (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Not urinating

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Biting - pruritus (se… · near591Not urinating · this reaction587Immediate pain upon i… · near586Oedema of the extremi… · near585Recovery prolonged · near585Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Not urinating

What the FDA AER plate says about Not urinating

Signature read: 136 death-coded reports is a heavy tail count for Not urinating in the CVM extract. Report volume is upper-third scale: 587 named reports in the openFDA extract. 136 of 587 reports were death-coded (23.2% of named reports, not a population mortality rate). Nearest volume peer: Immediate pain upon injection (±1 reports). Lead species Dog (337). Lead co-reported drug Buprenorphine (106).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Buprenorphine appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 337
Cat 246
Horse 3
Human 1

Breeds Most Affected

Domestic Shorthair 147
Retriever - Labrador 37
Cat (unknown) 24
Chihuahua 23
Domestic Longhair 22
Domestic Mediumhair 22
Shih Tzu 18
Crossbred Canine/dog 15
Terrier - Yorkshire 14
Shepherd Dog - German 14

Associated Drugs

Buprenorphine 106
Maropitant Citrate 88
Bedinvetmab 63
Gabapentin 58
Carprofen 41
Robenacoxib 37
Cefovecin 33
Afoxolaner 31
Frunevetmab 24
Diphenhydramine 23
Famotidine 21
Mirtazapine 20
Pyrantel Pamoate;Sarolaner 19
Isoflurane 19
Oclacitinib Maleate 18
Nitenpyram 18
Cefovecin Sodium 18
Dexmedetomidine 18
Butorphanol 18
Prednisone 17

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Not urinating, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (23.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Not urinating (#581 of 2,481 by report volume); death-coded 23.2%. PlainBreed reaction plate · death-coded report count stamp 136 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →