Not urinating

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VeDDRA Code: 2520

533 adverse event reports referencing this reaction

533
Total Reports
122
Deaths
2290.0%
Death Rate

Species Most Affected

Dog 315
Cat 216
Horse 1
Human 1

Breeds Most Affected

Domestic Shorthair 131
Retriever - Labrador 32
Cat (unknown) 23
Chihuahua 19
Domestic Mediumhair 19
Shih Tzu 18
Domestic Longhair 18
Crossbred Canine/dog 15
Terrier - Yorkshire 14
Shepherd Dog - German 12

Associated Drugs

Buprenorphine 93
Maropitant Citrate 75
Bedinvetmab 58
Gabapentin 47
Carprofen 40
Cefovecin 31
Afoxolaner 30
Robenacoxib 28
Frunevetmab 23
Pyrantel Pamoate;Sarolaner 18
Nitenpyram 17
Propofol 17
Isoflurane 17
Oclacitinib Maleate 16
Fluralaner Spot-On Solution 15
Prednisone 15
Famotidine 14
Milbemycin Oxime + Spinosad 14
Fluid Therapy 14
Dexmedetomidine 14

Data Summary

Metric Value
Total reports referencing reaction 533
Reports with fatal outcome 122
Case-fatality rate (reported events) 2290.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2520.

Not urinating Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 533 adverse event reports that reference Not urinating as a reaction term, including 122 reports with a death outcome — a 2290.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2520, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Not urinating appears most frequently in reports for Dog (315 reports), Cat (216 reports), Horse (1 reports) — with Dog dominating at 315 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (131), Retriever - Labrador (32), Cat (unknown) (23). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Not urinating are Buprenorphine (93 reports), Maropitant Citrate (75 reports), Bedinvetmab (58 reports), Gabapentin (47 reports), with Buprenorphine appearing alongside this reaction in 93 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial