Reaction profile

The FDA adverse-event record for not urinating

533 FDA adverse-event reports reference not urinating (VeDDRA 2520). See the species, breeds, and drugs most associated with it below.

533
reports citing this reaction
22.9%
death-coded share
Dog
most-affected species
Buprenorphine
most-associated drug
Verify with FDA CVM →
533
Total Reports
122
Deaths
22.9%
Death Rate

Species Most Affected

Dog 315
Cat 216
Horse 1
Human 1

Breeds Most Affected

Domestic Shorthair 131
Retriever - Labrador 32
Cat (unknown) 23
Chihuahua 19
Domestic Mediumhair 19
Shih Tzu 18
Domestic Longhair 18
Crossbred Canine/dog 15
Terrier - Yorkshire 14
Shepherd Dog - German 12

Associated Drugs

Buprenorphine 93
Maropitant Citrate 75
Bedinvetmab 58
Gabapentin 47
Carprofen 40
Cefovecin 31
Afoxolaner 30
Robenacoxib 28
Frunevetmab 23
Pyrantel Pamoate;Sarolaner 18
Nitenpyram 17
Propofol 17
Isoflurane 17
Oclacitinib Maleate 16
Fluralaner Spot-On Solution 15
Prednisone 15
Famotidine 14
Milbemycin Oxime + Spinosad 14
Fluid Therapy 14
Dexmedetomidine 14

Not urinating Reaction Insights

533 reports name Not urinating; 122 recorded a death outcome (22.9% of reported events, not a population-level mortality rate). VeDDRA code: 2520.

By species: Dog (315 reports), Cat (216 reports), Horse (1 reports). By breed: Domestic Shorthair (131), Retriever - Labrador (32), Cat (unknown) (23).

Most co-reported drugs: Buprenorphine (93 reports), Maropitant Citrate (75 reports), Bedinvetmab (58 reports), Gabapentin (47 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.