Panleucopenia

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VeDDRA Code: 169

66 adverse event reports referencing this reaction

66
Total Reports
25
Deaths
3790.0%
Death Rate

Species Most Affected

Dog 42
Cat 23
Other Canids 1

Breeds Most Affected

Domestic Shorthair 13
Retriever - Labrador 8
Maltese 3
Terrier - Bull - American Pit 3
Persian 2
Shih Tzu 2
Shepherd Dog - Australian 2
Terrier - Yorkshire 2
Bulldog 2
Bengal 2

Associated Drugs

Cefovecin 12
Maropitant Citrate 12
Oclacitinib Maleate 11
Moxidectin 6
Enrofloxacin 5
Selamectin 5
Carprofen 5
Feline Calicivirus, Strain F-9, Passage 7, Lot A; Feline Panleukopenia Virus, St 4
Dexamethasone 3
Famotidine 3
Ampicillin Sodium & Sulbactam Sodium 3
Doxycycline 3
Ampicillin 3
Anti-Il31 Mab Mcs Lot #1283563 3
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 3
Methylprednisolone Acetate 2
Buprenorphine 2
Triamcinolone 2
Marbofloxacin 2
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 2

Data Summary

Metric Value
Total reports referencing reaction 66
Reports with fatal outcome 25
Case-fatality rate (reported events) 3790.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 169.

Panleucopenia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 66 adverse event reports that reference Panleucopenia as a reaction term, including 25 reports with a death outcome — a 3790.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 169, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Panleucopenia appears most frequently in reports for Dog (42 reports), Cat (23 reports), Other Canids (1 reports) — with Dog dominating at 42 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (13), Retriever - Labrador (8), Maltese (3). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Panleucopenia are Cefovecin (12 reports), Maropitant Citrate (12 reports), Oclacitinib Maleate (11 reports), Moxidectin (6 reports), with Cefovecin appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial