Reaction profile

The FDA adverse-event record for tongue disorder nos

649 FDA reports name tongue disorder nos, a high-volume reaction in the CVM extract (VeDDRA 1845). Plate stamps and neighbourhood peers follow.

#539 of 2,481
by report volume (all reactions)
649
reports citing this reaction
18.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tongue disorder NOS has 649 reports now versus 634 in that prior snapshot: 15 more (2.4%).

Report change
+15
Death-coded reports
+2
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tongue disorder NOS changes

FDA AER · VeDDRA plate

Code 1845 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 649 reports
  • DEATH-ELEV 18.8%
  • UPPER-Q #539/2481
  • PHOTO-FINISH Liver failure
  • SPECIES-DOG Dog · 427
  • DRUG-LEAD Milbemycin Oxime… · 52
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Liver failure (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Tongue disorder NOS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Dull · near652Tongue disorder NOS · this r…649Liver failure · near648Patient instructions… · near647Temporary deafness · near647Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tongue disorder NOS

What the FDA AER plate says about Tongue disorder NOS

Signature read: 122 death-coded reports is a heavy tail count for Tongue disorder NOS in the CVM extract. Report volume is upper-third scale: 649 named reports in the openFDA extract. 122 of 649 reports were death-coded (18.8% of named reports, not a population mortality rate). Nearest volume peer: Liver failure (±1 reports). Lead species Dog (427). Lead co-reported drug Milbemycin Oxime + Spinosad (52).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 427
Cat 130
Horse 53
Human 36
Cattle 3

Breeds Most Affected

Domestic Shorthair 60
Retriever - Labrador 53
Unknown 38
Crossbred Canine/dog 35
Retriever - Golden 27
Chihuahua 22
Quarter Horse 19
Maltese 18
Terrier - Yorkshire 16
Shih Tzu 16

Associated Drugs

Milbemycin Oxime + Spinosad 52
Carprofen 51
Maropitant Citrate 43
Afoxolaner 39
Oclacitinib Maleate 37
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 26
Spinosad 25
Nitenpyram 24
Moxidectin 22
Bedinvetmab 22
Selamectin 21
Buprenorphine 21
Gabapentin 21
Cefovecin 19
Pyrantel Pamoate;Sarolaner 19
Meloxicam 18
Enrofloxacin 17
Isoflurane 17
Ivermectin 16
Fluralaner 13.64% 12-Week Chew 16

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Tongue disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (649 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tongue disorder NOS (#539 of 2,481 by report volume); death-coded 18.8%. PlainBreed reaction plate · death-coded report count stamp 122 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →