Reaction profile

The FDA adverse-event record for tongue disorder nos

617 FDA adverse-event reports reference tongue disorder nos (VeDDRA 1845). See the species, breeds, and drugs most associated with it below.

617
reports citing this reaction
19.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
617
Total Reports
117
Deaths
19.0%
Death Rate

Species Most Affected

Dog 409
Cat 121
Horse 49
Human 35
Cattle 3

Breeds Most Affected

Domestic Shorthair 57
Retriever - Labrador 52
Unknown 37
Crossbred Canine/dog 33
Retriever - Golden 27
Chihuahua 21
Maltese 18
Quarter Horse 17
Shepherd Dog - German 15
Shih Tzu 15

Associated Drugs

Milbemycin Oxime + Spinosad 52
Carprofen 49
Maropitant Citrate 42
Oclacitinib Maleate 37
Afoxolaner 37
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 26
Spinosad 25
Nitenpyram 24
Selamectin 21
Moxidectin 20
Buprenorphine 20
Cefovecin 18
Bedinvetmab 18
Meloxicam 17
Enrofloxacin 17
Isoflurane 17
Ivermectin 16
Gabapentin 16
Fluralaner 13.64% 12-Week Chew 16
Pyrantel Pamoate;Sarolaner 16

Tongue disorder NOS Reaction Insights

617 reports name Tongue disorder NOS; 117 recorded a death outcome (19.0% of reported events, not a population-level mortality rate). VeDDRA code: 1845.

By species: Dog (409 reports), Cat (121 reports), Horse (49 reports). By breed: Domestic Shorthair (57), Retriever - Labrador (52), Unknown (37).

Most co-reported drugs: Milbemycin Oxime + Spinosad (52 reports), Carprofen (49 reports), Maropitant Citrate (42 reports), Oclacitinib Maleate (37 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.