Reaction profile

The FDA adverse-event record for application site serosanguinous discharge

63 FDA adverse-event reports reference application site serosanguinous discharge (VeDDRA 33). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1624 of 2,481
by report volume (all reactions)
63
reports citing this reaction
4.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Application site serosanguinous discharge has 63 reports now versus 63 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Application site serosanguinous discharge changes

FDA AER · VeDDRA plate

Code 33 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 63 reports
  • DEATH-LOW 4.8%
  • MID-PACK #1624/2481
  • PHOTO-FINISH Circulatory disorder…
  • SPECIES-DOG Dog · 31
  • DRUG-LEAD Selamectin · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Circulatory disorder NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Application site serosanguinous discharge

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site sero… · thi…63Circulatory disorder… · near63DEATH-SLAUGHTERED · near63Hepatic lipidosis (st… · near63Monoparesis (paralysi… · near63Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Application site serosanguinous discharge

Application site serosanguinous discharge: low death-coded share in the FDA AER plate

Signature read: 3 death-coded reports is a thin tail count for Application site serosanguinous discharge in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 3 of 63 reports (4.8% of named reports). Nearest volume peer: Circulatory disorder NOS (±0 reports). Lead species Dog (31). Lead co-reported drug Selamectin (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 31
Cat 31
Horse 1

Breeds Most Affected

Domestic Shorthair 22
Crossbred Canine/dog 5
Domestic Longhair 4
Retriever - Labrador 3
Domestic Mediumhair 2
Retriever - Golden 2
Shepherd Dog - German 2
Shepherd Dog - Australian 1
Mixed (Dog) 1
Hound - Basset 1

Associated Drugs

Selamectin 14
Imidacloprid + Moxidectin 9
Bupivacaine Lipsome Injectable Suspension 9
Hydromorphone 9
Acepromazine 9
Isoflurane 9
Diazepam 8
Propfol 8
Oxygen 8
Morphine 8
Cefazolin 8
Hydromorphone/Lidocaine/Ketamine Cri 8
Tramadol 8
Carprofen 8
Cefpodoxime 8
Flumethrin-Imidacloprid 7
Selamectin;Sarolaner 7
Enrofloxacin 4
Prednisone 4
Emodepside + Praziquantel 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Application site serosanguinous discharge, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Application site serosanguinous discharge (#1624 of 2,481 by report volume); death-coded 4.8%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →