Reaction profile

The FDA adverse-event record for decreased red cell distribution width (rdw)

Name: Decreased red cell distribution width (RDW) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

11 FDA reports name decreased red cell distribution width (rdw), a lower-volume reaction in the CVM extract (VeDDRA 2858). Plate stamps and neighbourhood peers follow.

#2412 of 2,481
by report volume (all reactions): 11
reports citing this reaction: 18.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

FDA AER · VeDDRA plate

Code 2858 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 11 reports
DEATH-ELEV 18.2%
BOTTOM-DECILE #2412/2481
PHOTO-FINISH ABNORMAL PANCREATIC S…
SPECIES-DOG Dog · 7
DRUG-LEAD Clodronate Disodi… · 3
DESK-WIDE 9 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Decreased red cell distribution width

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Decreased red cell distribution width (RDW)

What the FDA AER plate says about Decreased red cell distribution width (RDW)

Signature read: 11 reports place Decreased red cell distribution width (RDW) in the lower third of FDA AER volume (#2412 of 2,481). Report volume is lower-third scale: 11 named reports in the openFDA extract. 2 of 11 reports were death-coded (18.2% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports). Lead species Dog (7). Lead co-reported drug Clodronate Disodium (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Clodronate Disodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7

Horse 3

Cat 1

Breeds Most Affected

Quarter Horse 3

Retriever - Chesapeake Bay 1

Domestic Shorthair 1

Pointing Dog - Hungarian Short-haired (Vizsla) 1

Terrier - Bull - American Pit 1

Retriever - Labrador 1

Spaniel - Cocker English 1

Dog (other) 1

Shepherd Dog - Australian 1

Associated Drugs

Clodronate Disodium 3

Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride 3

Water, Sodium Chloride 3

Furosemide 3

Acetaminophen 3

Verdinexor 2

Omeprazole 2

Flunixin 2

Hyaluronic Acid 2

Robenacoxib 1

Rabies Vaccine, Killed Virus 1

Cefovecin Sodium 1

Diphenhydramine Hydrochloride 1

Dexamethasone Sodium Phosphate 1

Epinephrine 1

Diphenhydramine 1

Amoxicillin + Potassium Clavulanate 1

Epoetin Alfa 1

Antiparasitic Collar 1

Enrofloxacin 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decreased red cell distribution width (RDW) (#2412 of 2,481 by report volume); death-coded 18.2%. PlainBreed reaction plate · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →