Reaction profile

The FDA adverse-event record for apnoea

967 FDA reports name apnoea, a high-volume reaction in the CVM extract (VeDDRA 830). Plate stamps and neighbourhood peers follow.

#403 of 2,481
by report volume (all reactions)
967
reports citing this reaction
53.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Apnoea has 967 reports now versus 960 in that prior snapshot: 7 more (0.7%).

Report change
+7
Death-coded reports
+3
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Apnoea changes

FDA AER · VeDDRA plate

Code 830 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 967 reports
  • DEATH-HOT 53.9%
  • UPPER-Q #403/2481
  • PHOTO-FINISH Necropsy performed
  • SPECIES-DOG Dog · 616
  • DRUG-LEAD Dexmedetomidine H… · 167
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Necropsy performed (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Apnoea

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal movement NOS · near978Rubbing · near969Apnoea · this reaction967Necropsy performed · near967Impaired vision · near963Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Apnoea

Apnoea: high death-coded share in the FDA AER plate

Signature read: 521 death-coded reports is a heavy tail count for Apnoea in the CVM extract. Report volume is upper-third scale: 967 named reports in the openFDA extract. Death-coded share is upper-third: 521 of 967 reports (53.9% of named reports). Nearest volume peer: Necropsy performed (±0 reports). Lead species Dog (616). Lead co-reported drug Dexmedetomidine Hydrochloride (167).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 616
Cat 283
Other 17
Horse 16
Rabbit 8
Mouse 4
Turtle 4
Goat 2
Cattle 2
Alpaca 2

Breeds Most Affected

Domestic (unspecified) 105
Dog (unknown) 65
Domestic Shorthair 65
Cat (unknown) 55
Crossbred Canine/dog 52
Retriever - Labrador 41
Unknown 38
Chihuahua 36
Shih Tzu 36
Retriever - Golden 18

Associated Drugs

Dexmedetomidine Hydrochloride 167
Isoflurane 159
Propofol 159
Ketamine Hydrochloride 96
Butorphanol 91
Butorphanol Tartrate 58
Ketamine 49
Alfaxalone 49
Dexmedetomidine 49
Carprofen 44
Midazolam 39
Sevoflurane 34
Maropitant Citrate 33
Hydromorphone 30
Buprenorphine 30
Tiletamine, Zolazepam 28
Acepromazine Maleate 27
Atipamezole Hydrochloride 26
Acepromazine 24
Gabapentin 22

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Apnoea, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (967 here).

Similar death-coded share

Nearest other reactions by death-coded share (53.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Apnoea (#403 of 2,481 by report volume); death-coded 53.9%. PlainBreed reaction plate · death-coded report count stamp 521 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →