Reaction profile
The FDA adverse-event record for large platelets
126 FDA adverse-event reports reference large platelets (VeDDRA 2425). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.
- #1284 of 2,481
- by report volume (all reactions)
- 126
- reports citing this reaction
- 23.8%
- death-coded share
- Dog
- most-affected species
Release-over-release change
What changed in the latest FDA data snapshot
PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Large platelets has 126 reports now versus 114 in that prior snapshot: 12 more (10.5%).
- Report change
- +12
- Death-coded reports
- +2
- Death-coded share
- −0.8 pts
This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.
Subscribe to Large platelets changesFDA AER · VeDDRA plate
Code 2425 VOL-LOW
VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL
- VOL-LOW 126 reports
- DEATH-HOT 23.8%
- MID-PACK #1284/2481
- PHOTO-FINISH Extensor rigidity
- SPECIES-DOG Dog · 121
- DRUG-LEAD Carprofen · 35
- DESK-WIDE 20 breeds
- BOOK-FULL 8/8 fields
Nearest volume peer: Extensor rigidity (±0 reports)
Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.
Report-volume neighbourhood around Large platelets
Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.
What the FDA AER plate says about Large platelets
Signature read: Large platelets's 23.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. 30 of 126 reports were death-coded (23.8% of named reports, not a population mortality rate). Nearest volume peer: Extensor rigidity (±0 reports). Lead species Dog (121). Lead co-reported drug Carprofen (35).
Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.
Species Most Affected
Breeds Most Affected
Associated Drugs
Nationwide reactions with similar profiles
Two openFDA-derived peer sets for Large platelets, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).
Similar report volume
Nearest other reactions by FDA report count (126 here).
Similar death-coded share
Nearest other reactions by death-coded share (23.8% here), distinct from the volume row.
What to do with this reaction
- Compare Large platelets's report profile against similar reactions nationwide. See similar reactions
- Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
- Browse the full reaction directory to compare report counts across reaction types. All reactions
A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →