Reaction profile

The FDA adverse-event record for duodenal ulcer

193 FDA adverse-event reports reference duodenal ulcer (VeDDRA 1088). See the species, breeds, and drugs most associated with it below.

193
reports citing this reaction
46.1%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
193
Total Reports
89
Deaths
46.1%
Death Rate

Species Most Affected

Dog 185
Cat 5
Horse 2
Other 1

Breeds Most Affected

Retriever - Labrador 43
Rottweiler 18
Boxer (German Boxer) 12
Crossbred Canine/dog 10
Retriever - Golden 10
Shepherd Dog - German 7
Mastiff 6
Beagle 5
Saint Bernard Dog 5
Siberian Husky 5

Associated Drugs

Carprofen 70
Deracoxib 48
Maropitant Citrate 33
Firocoxib 30
Tramadol 26
Firocoxib 227 Mg Chewable 24
Cephalexin 18
Meloxicam 16
Gabapentin 15
Isoflurane 14
Buprenorphine 13
Acepromazine 11
Cefazolin 11
Propofol 11
Grapiprant 11
Ketamine 10
Enrofloxacin 10
Fentanyl 8
Anesthetic 8
Midazolam 8

Duodenal ulcer Reaction Insights

193 reports name Duodenal ulcer; 89 recorded a death outcome (46.1% of reported events, not a population-level mortality rate). VeDDRA code: 1088.

By species: Dog (185 reports), Cat (5 reports), Horse (2 reports). By breed: Retriever - Labrador (43), Rottweiler (18), Boxer (German Boxer) (12).

Most co-reported drugs: Carprofen (70 reports), Deracoxib (48 reports), Maropitant Citrate (33 reports), Firocoxib (30 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.