Reaction profile

The FDA adverse-event record for duodenal ulcer

198 FDA adverse-event reports reference duodenal ulcer (VeDDRA 1088). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1043 of 2,481
by report volume (all reactions)
198
reports citing this reaction
47.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Duodenal ulcer has 198 reports now versus 195 in that prior snapshot: 3 more (1.5%).

Report change
+3
Death-coded reports
+2
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Duodenal ulcer changes

FDA AER · VeDDRA plate

Code 1088 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 198 reports
  • DEATH-HOT 47.0%
  • MID-PACK #1043/2481
  • PHOTO-FINISH Drowsiness - systemic…
  • SPECIES-DOG Dog · 190
  • DRUG-LEAD Carprofen · 73
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Drowsiness - systemic disorder (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Duodenal ulcer

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Drowsiness - systemic… · near198Duodenal ulcer · this reacti…198Haemolysis · near198INEFFECTIVE, EAR MITES · near198Stomach pain · near198Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Duodenal ulcer

Duodenal ulcer: high death-coded share in the FDA AER plate

Signature read: Duodenal ulcer's 47.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 93 of 198 reports (47.0% of named reports). Nearest volume peer: Drowsiness - systemic disorder (±0 reports). Lead species Dog (190). Lead co-reported drug Carprofen (73).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 190
Cat 5
Horse 2
Other 1

Breeds Most Affected

Retriever - Labrador 45
Rottweiler 18
Boxer (German Boxer) 12
Crossbred Canine/dog 10
Retriever - Golden 10
Shepherd Dog - German 7
Mastiff 6
Beagle 5
Saint Bernard Dog 5
Dog (unknown) 5

Associated Drugs

Carprofen 73
Deracoxib 48
Maropitant Citrate 34
Firocoxib 30
Tramadol 26
Firocoxib 227 Mg Chewable 24
Meloxicam 19
Cephalexin 18
Isoflurane 17
Gabapentin 15
Propofol 13
Buprenorphine 13
Acepromazine 11
Cefazolin 11
Grapiprant 11
Ketamine 10
Enrofloxacin 10
Anesthetic 8
Fentanyl 8
Midazolam 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Duodenal ulcer, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (198 here).

Similar death-coded share

Nearest other reactions by death-coded share (47.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Duodenal ulcer (#1043 of 2,481 by report volume); death-coded 47.0%. PlainBreed reaction plate · death-coded share stamp 47.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →