Reaction profile

The FDA adverse-event record for epistaxis (bilateral)

29 FDA adverse-event reports reference epistaxis (bilateral) (VeDDRA 2484). See the species, breeds, and drugs most associated with it below.

29
reports citing this reaction
27.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
29
Total Reports
8
Deaths
27.6%
Death Rate

Species Most Affected

Dog 25
Horse 3
Cattle 1

Breeds Most Affected

Shepherd Dog - German 2
Rottweiler 2
Retriever - Labrador 2
Pit Bull 2
Brittany 2
Pony (unspecified) 1
Terrier (unspecified) 1
Bulldog 1
Newfoundland 1
Terrier - Bull - Staffordshire 1

Associated Drugs

Oclacitinib Maleate 5
Carprofen 5
Maropitant Citrate 3
Moxidectin 3
Dexmedetomidine Hydrochloride 2
Cephalexin 2
Milbemycin Oxime + Praziquantel 2
Rabies Vaccine 2
Pergolide Mesylate 2
Anti-Il31 Mab Mcs Lot #1283563 2
Afoxolaner 2
Melarsomine Dihydrochloride 2
Firocoxib 2
Trilostane 2
Polysulfated Glycosaminoglycan 2
Omeprazole 2
Propofol 2
Prednisone 2
Gabapentin 2
Butorphanol 2

Epistaxis (bilateral) Reaction Insights

29 reports name Epistaxis (bilateral); 8 recorded a death outcome (27.6% of reported events, not a population-level mortality rate). VeDDRA code: 2484.

By species: Dog (25 reports), Horse (3 reports), Cattle (1 reports). By breed: Shepherd Dog - German (2), Rottweiler (2), Retriever - Labrador (2).

Most co-reported drugs: Oclacitinib Maleate (5 reports), Carprofen (5 reports), Maropitant Citrate (3 reports), Moxidectin (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.