Reaction profile

The FDA adverse-event record for epistaxis (bilateral)

31 FDA reports name epistaxis (bilateral), a lower-volume reaction in the CVM extract (VeDDRA 2484). Plate stamps and neighbourhood peers follow.

#1972 of 2,481
by report volume (all reactions)
31
reports citing this reaction
32.3%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Epistaxis (bilateral) has 31 reports now versus 30 in that prior snapshot: 1 more (3.3%).

Report change
+1
Death-coded reports
+1
Death-coded share
+2.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Epistaxis (bilateral) changes

FDA AER · VeDDRA plate

Code 2484 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-HOT 32.3%
  • LOWER-Q #1972/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-DOG Dog · 27
  • DRUG-LEAD Oclacitinib Malea… · 5
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Epistaxis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31Epistaxis (bilateral) · this…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Epistaxis (bilateral)

Epistaxis (bilateral): high death-coded share in the FDA AER plate

Signature read: 31 reports place Epistaxis (bilateral) in the lower third of FDA AER volume (#1972 of 2,481). Report volume is lower-third scale: 31 named reports in the openFDA extract. Death-coded share is upper-third: 10 of 31 reports (32.3% of named reports). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (27). Lead co-reported drug Oclacitinib Maleate (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 27
Horse 3
Cattle 1

Breeds Most Affected

Shepherd Dog - German 2
Rottweiler 2
Retriever - Labrador 2
Pit Bull 2
Brittany 2
Pony (unspecified) 1
Terrier (unspecified) 1
Bulldog 1
Newfoundland 1
Terrier - Bull - Staffordshire 1

Associated Drugs

Oclacitinib Maleate 5
Carprofen 5
Maropitant Citrate 4
Anti-Il31 Mab Mcs Lot #1283563 3
Moxidectin 3
Prednisone 3
Gabapentin 3
Isoflurane 3
Dexmedetomidine Hydrochloride 2
Cephalexin 2
Cefpodoxime 2
Milbemycin Oxime + Praziquantel 2
Rabies Vaccine 2
Pergolide Mesylate 2
Afoxolaner 2
Melarsomine Dihydrochloride 2
Firocoxib 2
Polysulfated Glycosaminoglycan 2
Trilostane 2
Omeprazole 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Epistaxis (bilateral) (#1972 of 2,481 by report volume); death-coded 32.3%. PlainBreed reaction plate · report volume stamp 31 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →