Reaction profile

The FDA adverse-event record for neutropenia

2,131 FDA adverse-event reports reference neutropenia (VeDDRA 167). See the species, breeds, and drugs most associated with it below.

2,131
reports citing this reaction
17.8%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
2,131
Total Reports
380
Deaths
17.8%
Death Rate

Species Most Affected

Dog 1,695
Cat 392
Horse 41
Cattle 1
Alpaca 1
Lynx 1

Breeds Most Affected

Domestic Shorthair 240
Retriever - Labrador 210
Retriever - Golden 111
Crossbred Canine/dog 100
Terrier - Yorkshire 54
Shepherd Dog - German 47
Shih Tzu 46
Terrier - Bull - American Pit 46
Beagle 45
Maltese 45

Associated Drugs

Oclacitinib Maleate 561
Maropitant Citrate 197
Carprofen 170
Cefovecin 95
Prednisone 92
Gabapentin 86
Afoxolaner 83
Toceranib Phosphate 76
Enrofloxacin 76
Buprenorphine 74
Milbemycin Oxime + Spinosad 71
Cyclosporine 69
Metronidazole 66
Ivermectin + Pyrantel As Pamoate Salt 66
Ilunocitinib 66
Famotidine 63
Moxidectin 60
Anti-Il31 Mab Mcs Lot #1283563 59
Meloxicam 54
Rabacfosadine Succinate 45

Neutropenia Reaction Insights

2,131 reports name Neutropenia; 380 recorded a death outcome (17.8% of reported events, not a population-level mortality rate). VeDDRA code: 167.

By species: Dog (1,695 reports), Cat (392 reports), Horse (41 reports). By breed: Domestic Shorthair (240), Retriever - Labrador (210), Retriever - Golden (111).

Most co-reported drugs: Oclacitinib Maleate (561 reports), Maropitant Citrate (197 reports), Carprofen (170 reports), Cefovecin (95 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.