Reaction profile

The FDA adverse-event record for laceration

167 FDA adverse-event reports reference laceration (VeDDRA 2509). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1136 of 2,481
by report volume (all reactions)
167
reports citing this reaction
12.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Laceration has 167 reports now versus 164 in that prior snapshot: 3 more (1.8%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Laceration changes

FDA AER · VeDDRA plate

Code 2509 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 167 reports
  • DEATH-ELEV 12.6%
  • MID-PACK #1136/2481
  • PHOTO-FINISH Increased band neutro…
  • SPECIES-DOG Dog · 106
  • DRUG-LEAD Milbemycin Oxime… · 28
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Increased band neutrophilia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Laceration

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Hyperkeratosis · near168Involuntary movement · near168Tingling sensation · near168Increased band neutro… · near167Laceration · this reaction167Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Laceration

What the FDA AER plate says about Laceration

Signature read: death-coded share at 12.6% is the most distinctive outcome stamp on Laceration. Report volume sits in the middle third of the reaction corpus. 21 of 167 reports were death-coded (12.6% of named reports, not a population mortality rate). Nearest volume peer: Increased band neutrophilia (±0 reports). Lead species Dog (106). Lead co-reported drug Milbemycin Oxime + Spinosad (28).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 106
Human 21
Cat 19
Cattle 7
Horse 6
Pig 3
Unknown 3
Chicken 2

Breeds Most Affected

Unknown 24
Retriever - Labrador 17
Domestic Shorthair 13
Dog (unknown) 8
Crossbred Canine/dog 7
Retriever - Golden 6
Greyhound 6
Collie - Border 5
Shih Tzu 5
Shepherd Dog - German 4

Associated Drugs

Milbemycin Oxime + Spinosad 28
Milbemycin Oxime + Praziquantel 23
Imidacloprid + Moxidectin 18
Afoxolaner 13
Gabapentin 11
Lotilaner 10
Moxidectin 9
Buprenorphine 9
Carprofen 8
Robenacoxib 8
Bedinvetmab 8
Fluralaner Chew Tablets 7
Dexmedetomidine 7
Nitenpyram 6
Bovine Rhinotracheitis-Virus Diarrhea-Parainfluenza3-Respiratory Syncytial Virus Vaccine 6
Tylosin Phosphate 6
Propofol 6
Trilostane 5
Fenbendazole 5
Ivermectin + Pyrantel As Pamoate Salt 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Laceration, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (167 here).

Similar death-coded share

Nearest other reactions by death-coded share (12.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Laceration (#1136 of 2,481 by report volume); death-coded 12.6%. PlainBreed reaction plate · death-coded share stamp 12.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →