Reaction profile

The FDA adverse-event record for colic

732 FDA adverse-event reports reference colic (VeDDRA 264). See the species, breeds, and drugs most associated with it below.

732
reports citing this reaction
18.0%
death-coded share
Horse
most-affected species
Ceftiofur Crystalline Free Acid
most-associated drug
Verify with FDA CVM →
732
Total Reports
132
Deaths
18.0%
Death Rate

Species Most Affected

Horse 703
Dog 11
Cattle 9
Donkey 5
Mule 2
Other Equids 1
Alpaca 1

Breeds Most Affected

Quarter Horse 178
Horse (unknown) 130
Thoroughbred 87
Arab 44
Warmblood (unspecified) 41
Unknown 22
Paint 22
Tennessee Walking Horse 19
Warmblood - Dutch 18
Morgan 14

Associated Drugs

Ceftiofur Crystalline Free Acid 83
Pergolide Mesylate 59
Clodronate Disodium 57
Oxybendazole 56
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 47
Detomidine Hydrochloride 36
Praziquantel;Moxidectin 30
Omeprazole 37% Oral Paste 29
Polysulfated Glycosaminoglycan 25
Praziquantel; Moxidectin 25
Flunixin Meglumine 23
Moxidectin 23
Monensin Sodium 21
Omeprazole 20
Firocoxib 18
Flunixin Meglumine Injectable 18
Ivermectin + Praziquantel 18
Phenylbutazone 17
Banamine 15
N-Butylscopolaminium Bromide 14

Colic Reaction Insights

732 reports name Colic; 132 recorded a death outcome (18.0% of reported events, not a population-level mortality rate). VeDDRA code: 264.

By species: Horse (703 reports), Dog (11 reports), Cattle (9 reports). By breed: Quarter Horse (178), Horse (unknown) (130), Thoroughbred (87).

Most co-reported drugs: Ceftiofur Crystalline Free Acid (83 reports), Pergolide Mesylate (59 reports), Clodronate Disodium (57 reports), Oxybendazole (56 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.