Reaction profile

The FDA adverse-event record for ear irritation

212 FDA adverse-event reports reference ear irritation (VeDDRA 1436). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1000 of 2,481
by report volume (all reactions)
212
reports citing this reaction
3.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ear irritation has 212 reports now versus 209 in that prior snapshot: 3 more (1.4%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ear irritation changes

FDA AER · VeDDRA plate

Code 1436 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 212 reports
  • DEATH-LOW 3.8%
  • MID-PACK #1000/2481
  • PHOTO-FINISH Aspiration pneumonia
  • SPECIES-DOG Dog · 187
  • DRUG-LEAD Florfenicol + Mom… · 21
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Aspiration pneumonia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Ear irritation

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Aspiration pneumonia · near212Blood loss NOS · near212Ear irritation · this reacti…212INEFFECTIVE, ANALGESIA · near212Labels, Abnormal · near212Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ear irritation

Ear irritation: low death-coded share in the FDA AER plate

Signature read: Ear irritation's 3.8% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 8 of 212 reports (3.8% of named reports). Nearest volume peer: Aspiration pneumonia (±0 reports). Lead species Dog (187). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (21).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 187
Cat 24
Horse 1

Breeds Most Affected

Retriever - Golden 20
Crossbred Canine/dog 20
Retriever - Labrador 17
Domestic Shorthair 13
Shih Tzu 12
Dog (unknown) 6
Shepherd Dog - German 6
Terrier - Rat 6
Beagle 5
Terrier - Yorkshire 5

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 21
Milbemycin Oxime + Spinosad 19
Genta/Momet/Clotrim Ear Oint 17
Betamethasone + Florfenicol + Terbinafine 17
Oclacitinib Maleate 13
Afoxolaner 11
Meloxicam 9
Fluralaner Chew Tablets 8
Milbemycin Oxime + Praziquantel 8
Ivermectin + Pyrantel As Pamoate Salt 7
Maropitant Citrate 7
Tresaderm Dermatological Solution 6
Trilostane 6
Miconazole + Polymyxin B + Prednisolone 6
Prednisone 5
Diphenhydramine 5
Spinosad 4
Selamectin 4
Orbiflox/Momet/Posaco Eardrops 4
Carprofen 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ear irritation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (212 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ear irritation (#1000 of 2,481 by report volume); death-coded 3.8%. PlainBreed reaction plate · death-coded share stamp 3.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →