Reaction profile

The FDA adverse-event record for other immune system disorder nos

187 FDA adverse-event reports reference other immune system disorder nos (VeDDRA 522). See the species, breeds, and drugs most associated with it below.

187
reports citing this reaction
22.5%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
187
Total Reports
42
Deaths
22.5%
Death Rate

Species Most Affected

Dog 168
Cat 13
Human 3
Cattle 2
Horse 1

Breeds Most Affected

Retriever - Labrador 24
Dog (unknown) 17
Retriever - Golden 13
Shepherd Dog - German 12
Domestic Shorthair 6
Chihuahua 5
Rottweiler 5
Crossbred Canine/dog 4
Shar Pei 4
Boxer (German Boxer) 4

Associated Drugs

Oclacitinib Maleate 53
Milbemycin Oxime + Spinosad 24
Carprofen 15
Spinosad 12
Prednisone 12
Cyclosporine 11
Maropitant Citrate 10
Doxycycline 10
Moxidectin 9
Bedinvetmab 9
Tramadol 8
Anti-Il31 Mab Mcs Lot #1283563 8
Cefovecin 7
Sarolaner 6
Cefpodoxime Proxetil 5
Gabapentin 5
Fluralaner Chew Tablets 5
Afoxolaner 5
Pyrantel Pamoate;Sarolaner 5
Cephalexin 4

Other immune system disorder NOS Reaction Insights

187 reports name Other immune system disorder NOS; 42 recorded a death outcome (22.5% of reported events, not a population-level mortality rate). VeDDRA code: 522.

By species: Dog (168 reports), Cat (13 reports), Human (3 reports). By breed: Retriever - Labrador (24), Dog (unknown) (17), Retriever - Golden (13).

Most co-reported drugs: Oclacitinib Maleate (53 reports), Milbemycin Oxime + Spinosad (24 reports), Carprofen (15 reports), Spinosad (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.