Reaction profile

The FDA adverse-event record for other immune system disorder nos

192 FDA adverse-event reports reference other immune system disorder nos (VeDDRA 522). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1060 of 2,481
by report volume (all reactions)
192
reports citing this reaction
21.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Other immune system disorder NOS has 192 reports now versus 190 in that prior snapshot: 2 more (1.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Other immune system disorder NOS changes

FDA AER · VeDDRA plate

Code 522 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 192 reports
  • DEATH-HOT 21.9%
  • MID-PACK #1060/2481
  • PHOTO-FINISH Adaptor, breakage
  • SPECIES-DOG Dog · 172
  • DRUG-LEAD Oclacitinib Malea… · 55
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, breakage (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Other immune system disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiac murmur · near193Adaptor, breakage · near192Joint pain NOS · near192Other immune system d… · thi…192Bloody stool · near191Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Other immune system disorder NOS

What the FDA AER plate says about Other immune system disorder NOS

Signature read: 42 death-coded reports is a heavy tail count for Other immune system disorder NOS in the CVM extract. Report volume sits in the middle third of the reaction corpus. 42 of 192 reports were death-coded (21.9% of named reports, not a population mortality rate). Nearest volume peer: Adaptor, breakage (±0 reports). Lead species Dog (172). Lead co-reported drug Oclacitinib Maleate (55).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 172
Cat 14
Human 3
Cattle 2
Horse 1

Breeds Most Affected

Retriever - Labrador 24
Dog (unknown) 17
Retriever - Golden 13
Shepherd Dog - German 12
Domestic Shorthair 6
Chihuahua 5
Rottweiler 5
Crossbred Canine/dog 4
Shar Pei 4
Boxer (German Boxer) 4

Associated Drugs

Oclacitinib Maleate 55
Milbemycin Oxime + Spinosad 24
Carprofen 18
Prednisone 14
Spinosad 12
Maropitant Citrate 12
Cyclosporine 11
Doxycycline 10
Moxidectin 9
Anti-Il31 Mab Mcs Lot #1283563 9
Bedinvetmab 9
Tramadol 8
Cefovecin 7
Gabapentin 6
Sarolaner 6
Cefpodoxime Proxetil 5
Enrofloxacin 5
Fluralaner Chew Tablets 5
Afoxolaner 5
Pyrantel Pamoate;Sarolaner 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Other immune system disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (192 here).

Similar death-coded share

Nearest other reactions by death-coded share (21.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Other immune system disorder NOS (#1060 of 2,481 by report volume); death-coded 21.9%. PlainBreed reaction plate · death-coded report count stamp 42 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →