Reaction profile

The FDA adverse-event record for lack of efficacy (endoparasite) - strongylids

Name: Lack of efficacy (endoparasite) - strongylids - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

41 FDA reports name lack of efficacy (endoparasite) - strongylids, a lower-volume reaction in the CVM extract (VeDDRA 2825). Plate stamps and neighbourhood peers follow.

#1838 of 2,481
by report volume (all reactions): 41
reports citing this reaction: 7.3%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (endoparasite) - strongylids has 41 reports now versus 40 in that prior snapshot: 1 more (2.5%).

Report change: +1
Death-coded reports: +0
Death-coded share: −0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (endoparasite) - strongylids changes

FDA AER · VeDDRA plate

Code 2825 VOL-TRACE

VOL-TRACE · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 41 reports
DEATH-PAR 7.3%
MID-PACK #1838/2481
PHOTO-FINISH Hydrocephalus
SPECIES-DOG Dog · 19
DRUG-LEAD Praziquantel;Moxi… · 8
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Hydrocephalus (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - strongylids

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Lack of efficacy (endoparasite) - strongylids

Lack of efficacy (endoparasite) - strongylids: low death-coded share in the FDA AER plate

Signature read: 3 death-coded reports is a thin tail count for Lack of efficacy (endoparasite) - strongylids in the CVM extract. Report volume is lower-third scale: 41 named reports in the openFDA extract. Death-coded share is lower-third: 3 of 41 reports (7.3% of named reports). Nearest volume peer: Hydrocephalus (±0 reports). Lead species Dog (19). Lead co-reported drug Praziquantel;Moxidectin (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Praziquantel;Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 19

Horse 13

Cattle 5

Frog 1

Other 1

Sheep 1

Goat 1

Breeds Most Affected

Thoroughbred 3

Retriever - Golden 3

Catahoula Leopard Dog 3

Unknown 2

Crossbred Canine/dog 2

Crossbred Equine/horse 2

Cattle (other) 2

Horse (unknown) 2

Paint 2

Mustang 2

Associated Drugs

Praziquantel;Moxidectin 8

Moxidectin 7

Pyrantel Pamoate;Sarolaner 6

Fenbendazol Suspension 4

Milbemycin Oxime + Praziquantel 4

Panacur 4

Oxybendazole 4

Ivermectin Paste 1.87% 4

Ivermectin 3

Eprinomectin 3

Ivermectin + Pyrantel As Pamoate Salt 3

Fenbendazol Oral Paste 2

Ivermectin/Praziquantel 1

Milbemycin Oxime 1

Imidacloprid + Moxidectin 1

Febantel + Praziquantel + Pyrantel Pamoate 1

Fenbendazole 1

Doramectin 1

Afoxolaner 18.75Mg / Moxidectin 90Mcg / Pyrantel 37.5Mg Chewable Tablet 1

Milbemycin/Lufenuron/Pzq Chew 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (endoparasite) - strongylids (#1838 of 2,481 by report volume); death-coded 7.3%. PlainBreed reaction plate · death-coded report count stamp 3 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →