Abnormal movement NOS

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VeDDRA Code: 1131

943 adverse event reports referencing this reaction

943
Total Reports
167
Deaths
1770.0%
Death Rate

Species Most Affected

Dog 742
Cat 158
Horse 24
Cattle 8
Human 2
Ferret 2
Mouse 1
Chicken 1
Sheep 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 97
Retriever - Labrador 67
Crossbred Canine/dog 64
Retriever - Golden 41
Chihuahua 37
Shih Tzu 32
Shepherd Dog - German 25
Terrier - Yorkshire 22
Maltese 21
Boxer (German Boxer) 20

Associated Drugs

Milbemycin Oxime + Spinosad 125
Bedinvetmab 79
Fluralaner 13.64% 12-Week Chew 72
Sarolaner 60
Carprofen 46
Pyrantel Pamoate;Sarolaner 43
Afoxolaner 38
Ivermectin + Pyrantel As Pamoate Salt 36
Maropitant Citrate 35
Gabapentin 33
Oclacitinib Maleate 30
Spinosad 28
Cefovecin 28
Buprenorphine 28
Fluralaner Chew Tablets 28
Milbemycin Oxime + Praziquantel 25
Moxidectin 22
Propofol 20
Isoflurane 18
Prednisone 18

Data Summary

Metric Value
Total reports referencing reaction 943
Reports with fatal outcome 167
Case-fatality rate (reported events) 1770.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1131.

Abnormal movement NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 943 adverse event reports that reference Abnormal movement NOS as a reaction term, including 167 reports with a death outcome — a 1770.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1131, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Abnormal movement NOS appears most frequently in reports for Dog (742 reports), Cat (158 reports), Horse (24 reports) — with Dog dominating at 742 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (97), Retriever - Labrador (67), Crossbred Canine/dog (64). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Abnormal movement NOS are Milbemycin Oxime + Spinosad (125 reports), Bedinvetmab (79 reports), Fluralaner 13.64% 12-Week Chew (72 reports), Sarolaner (60 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 125 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial