Reaction profile

The FDA adverse-event record for abnormal movement nos

943 FDA adverse-event reports reference abnormal movement nos (VeDDRA 1131). See the species, breeds, and drugs most associated with it below.

943
reports citing this reaction
17.7%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
943
Total Reports
167
Deaths
17.7%
Death Rate

Species Most Affected

Dog 742
Cat 158
Horse 24
Cattle 8
Human 2
Ferret 2
Mouse 1
Chicken 1
Sheep 1
Rabbit 1

Breeds Most Affected

Domestic Shorthair 97
Retriever - Labrador 67
Crossbred Canine/dog 64
Retriever - Golden 41
Chihuahua 37
Shih Tzu 32
Shepherd Dog - German 25
Terrier - Yorkshire 22
Maltese 21
Boxer (German Boxer) 20

Associated Drugs

Milbemycin Oxime + Spinosad 125
Bedinvetmab 79
Fluralaner 13.64% 12-Week Chew 72
Sarolaner 60
Carprofen 46
Pyrantel Pamoate;Sarolaner 43
Afoxolaner 38
Ivermectin + Pyrantel As Pamoate Salt 36
Maropitant Citrate 35
Gabapentin 33
Oclacitinib Maleate 30
Spinosad 28
Cefovecin 28
Buprenorphine 28
Fluralaner Chew Tablets 28
Milbemycin Oxime + Praziquantel 25
Moxidectin 22
Propofol 20
Isoflurane 18
Prednisone 18

Abnormal movement NOS Reaction Insights

943 reports name Abnormal movement NOS; 167 recorded a death outcome (17.7% of reported events, not a population-level mortality rate). VeDDRA code: 1131.

By species: Dog (742 reports), Cat (158 reports), Horse (24 reports). By breed: Domestic Shorthair (97), Retriever - Labrador (67), Crossbred Canine/dog (64).

Most co-reported drugs: Milbemycin Oxime + Spinosad (125 reports), Bedinvetmab (79 reports), Fluralaner 13.64% 12-Week Chew (72 reports), Sarolaner (60 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.