Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - parvovirus (including feline panleukopenia)

310 FDA adverse-event reports reference lack of efficacy (virus) - parvovirus (including feline panleukopenia) (VeDDRA 2552). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#856 of 2,481
by report volume (all reactions)
310
reports citing this reaction
30.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (virus) - parvovirus (including feline panleukopenia) has 310 reports now versus 299 in that prior snapshot: 11 more (3.7%).

Report change
+11
Death-coded reports
+4
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (virus) - parvovirus (including feline panleukopenia) changes

FDA AER · VeDDRA plate

Code 2552 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 310 reports
  • DEATH-HOT 30.0%
  • MID-PACK #856/2481
  • PHOTO-FINISH Cloudy eye (for Miosi…
  • SPECIES-DOG Dog · 300
  • DRUG-LEAD Maropitant Citrate · 109
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see 'Neurological') (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Lack of efficacy - parvovirus

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Elevated haematocrit · near311Cloudy eye (for Miosi… · near310Cushings disease NOS · near310Labeled drug-species… · near310Lack of efficacy (vir… · thi…310Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (virus) - parvovirus (including feline panleukopenia)

Lack of efficacy (virus) - parvovirus (including feline panleukopenia): high death-coded share in the FDA AER plate

Signature read: 93 death-coded reports is a heavy tail count for Lack of efficacy (virus) - parvovirus (including feline panleukopenia) in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 93 of 310 reports (30.0% of named reports). Nearest volume peer: Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see 'Neurological') (±0 reports). Lead species Dog (300). Lead co-reported drug Maropitant Citrate (109).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 300
Cat 10

Breeds Most Affected

Retriever - Labrador 36
Retriever - Golden 21
Shepherd Dog - Australian 16
Crossbred Canine/dog 15
Shepherd Dog - German 14
Poodle - Standard 10
Poodle (unspecified) 9
Shih Tzu 9
Pit Bull 8
Mountain Dog - Bernese 8

Associated Drugs

Maropitant Citrate 109
Milbemycin Oxime + Praziquantel 76
Lotilaner 58
Fluid Therapy 50
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus 41
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 41
Enrofloxacin 39
Rabies Vaccine 38
Metronidazole 36
Afoxolaner 27
Canine Parvovirus Monoclonal Antibody 26
Ivermectin + Pyrantel As Pamoate Salt 23
Canine Da2Ppv (Orig S-P Us) Lv 23
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 21
Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine, Modified Live Virus, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 21
Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine, Modified Live Virus 21
Capromorelin Tartrate 21
Fenbendazol Granules 19
Metoclopramide 19
Canine Adenovirus, Type 2 Virus, V197 Strain,Canine Distemper Virus, Ondesterpoort Strain,Canine Parainfluenza, 91880 Strain,Canine Parvovirus, Fd 2001 Strain 19

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lack of efficacy (virus) - parvovirus (including feline panleukopenia), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (30.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (virus) - parvovirus (including feline panleukopenia) (#856 of 2,481 by report volume); death-coded 30.0%. PlainBreed reaction plate · death-coded report count stamp 93 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →