Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - parvovirus (including feline panleukopenia)

276 FDA adverse-event reports reference lack of efficacy (virus) - parvovirus (including feline panleukopenia) (VeDDRA 2552). See the species, breeds, and drugs most associated with it below.

276
reports citing this reaction
30.8%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
276
Total Reports
85
Deaths
30.8%
Death Rate

Species Most Affected

Dog 271
Cat 5

Breeds Most Affected

Retriever - Labrador 33
Retriever - Golden 20
Shepherd Dog - Australian 15
Crossbred Canine/dog 14
Shepherd Dog - German 11
Poodle - Standard 9
Pit Bull 8
Poodle (unspecified) 8
Mountain Dog - Bernese 8
Dog (unknown) 7

Associated Drugs

Maropitant Citrate 93
Milbemycin Oxime + Praziquantel 68
Lotilaner 52
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus 41
Fluid Therapy 40
Enrofloxacin 36
Metronidazole 34
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Mlv, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 32
Rabies Vaccine 28
Canine Parvovirus Monoclonal Antibody 25
Afoxolaner 23
Ivermectin + Pyrantel As Pamoate Salt 22
Canine Da2Ppv (Orig S-P Us) Lv 22
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 21
Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine, Modified Live Virus, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 21
Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine, Modified Live Virus 21
Capromorelin Tartrate 21
Fenbendazol Granules 19
Metoclopramide 18
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 18

Lack of efficacy (virus) - parvovirus (including feline panleukopenia) Reaction Insights

276 reports name Lack of efficacy (virus) - parvovirus (including feline panleukopenia); 85 recorded a death outcome (30.8% of reported events, not a population-level mortality rate). VeDDRA code: 2552.

By species: Dog (271 reports), Cat (5 reports). By breed: Retriever - Labrador (33), Retriever - Golden (20), Shepherd Dog - Australian (15).

Most co-reported drugs: Maropitant Citrate (93 reports), Milbemycin Oxime + Praziquantel (68 reports), Lotilaner (52 reports), Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus (41 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.