Reaction profile

The FDA adverse-event record for sensory abnormality nos

90 FDA adverse-event reports reference sensory abnormality nos (VeDDRA 1740). See the species, breeds, and drugs most associated with it below.

90
reports citing this reaction
5.6%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
90
Total Reports
5
Deaths
5.6%
Death Rate

Species Most Affected

Dog 42
Human 39
Cat 7
Unknown 1
Horse 1

Breeds Most Affected

Unknown 40
Retriever - Labrador 9
Crossbred Canine/dog 5
Chihuahua 4
Ragdoll 3
Domestic Shorthair 3
Shepherd Dog - German 3
Boxer (German Boxer) 2
Shih Tzu 2
Maltese 2

Associated Drugs

Milbemycin Oxime + Spinosad 11
Tilmicosin Phosphate 7
Selamectin 6
Grapiprant 6
Ketamine 5
Robenacoxib 5
Oclacitinib Maleate 4
Fluralaner Chew Tablets 4
Sarolaner 4
Isoflurane 4
Buprenorphine 4
Spinosad 3
Ivermectin 3
Carprofen 3
Mercaptobenzothiazole 3
Gabapentin 3
Dexmedetomidine 3
Bedinvetmab 3
Imidacloprid, Moxidectin 2
Copper Naphthenate 2

Sensory abnormality NOS Reaction Insights

90 reports name Sensory abnormality NOS; 5 recorded a death outcome (5.6% of reported events, not a population-level mortality rate). VeDDRA code: 1740.

By species: Dog (42 reports), Human (39 reports), Cat (7 reports). By breed: Unknown (40), Retriever - Labrador (9), Crossbred Canine/dog (5).

Most co-reported drugs: Milbemycin Oxime + Spinosad (11 reports), Tilmicosin Phosphate (7 reports), Selamectin (6 reports), Grapiprant (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.