Reaction profile

The FDA adverse-event record for photophobia

87 FDA adverse-event reports reference photophobia (VeDDRA 704). See the species, breeds, and drugs most associated with it below.

87
reports citing this reaction
6.9%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
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87
Total Reports
6
Deaths
6.9%
Death Rate

Species Most Affected

Dog 71
Cat 10
Human 6

Breeds Most Affected

Boxer (German Boxer) 9
Retriever - Labrador 7
Domestic Shorthair 6
Unknown 6
Crossbred Canine/dog 5
Terrier - Yorkshire 5
Chihuahua 3
Beagle 3
Domestic (unspecified) 2
Pit Bull 2

Associated Drugs

Milbemycin Oxime + Spinosad 32
Spinosad 7
Sarolaner 7
Prednisone 5
Cyclosporine 4
Imidacloprid + Moxidectin 3
Maropitant Citrate 3
Moxidectin 3
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 3
Meloxicam 2
Marbofloxacin 2
Enrofloxacin 2
Diphenhydramine 2
Ivermectin 2
Milbemycin Oxime, Lufenuron 2
Afoxolaner 136 Mg Chewable Tablets 2
Oclacitinib Maleate 2
Lotilaner 2
Selamectin 1
Melarsomine Dihydrochloride 1

Photophobia Reaction Insights

87 reports name Photophobia; 6 recorded a death outcome (6.9% of reported events, not a population-level mortality rate). VeDDRA code: 704.

By species: Dog (71 reports), Cat (10 reports), Human (6 reports). By breed: Boxer (German Boxer) (9), Retriever - Labrador (7), Domestic Shorthair (6).

Most co-reported drugs: Milbemycin Oxime + Spinosad (32 reports), Spinosad (7 reports), Sarolaner (7 reports), Prednisone (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.