Reaction profile

The FDA adverse-event record for photophobia

90 FDA adverse-event reports reference photophobia (VeDDRA 704). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1444 of 2,481
by report volume (all reactions)
90
reports citing this reaction
7.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Photophobia has 90 reports now versus 89 in that prior snapshot: 1 more (1.1%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Photophobia changes

FDA AER · VeDDRA plate

Code 704 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 90 reports
  • DEATH-PAR 7.8%
  • MID-PACK #1444/2481
  • PHOTO-FINISH Dermal nodule
  • SPECIES-DOG Dog · 74
  • DRUG-LEAD Milbemycin Oxime… · 32
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Dermal nodule (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Photophobia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site pyod… · near91Dermal nodule · near90Photophobia · this reaction90Skin haematoma · near90Cervical pain · near89Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Photophobia

Photophobia: low death-coded share in the FDA AER plate

Signature read: 7 death-coded reports is a thin tail count for Photophobia in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 7 of 90 reports (7.8% of named reports). Nearest volume peer: Dermal nodule (±0 reports). Lead species Dog (74). Lead co-reported drug Milbemycin Oxime + Spinosad (32).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 74
Cat 10
Human 6

Breeds Most Affected

Boxer (German Boxer) 9
Retriever - Labrador 8
Domestic Shorthair 6
Unknown 6
Crossbred Canine/dog 5
Terrier - Yorkshire 5
Chihuahua 3
Beagle 3
Terrier - Jack Russell 3
Domestic (unspecified) 2

Associated Drugs

Milbemycin Oxime + Spinosad 32
Spinosad 7
Sarolaner 7
Prednisone 5
Cyclosporine 4
Imidacloprid + Moxidectin 3
Maropitant Citrate 3
Moxidectin 3
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 3
Meloxicam 2
Marbofloxacin 2
Enrofloxacin 2
Diphenhydramine 2
Ivermectin 2
Milbemycin Oxime, Lufenuron 2
Afoxolaner 136 Mg Chewable Tablets 2
Afoxolaner 2
Oclacitinib Maleate 2
Pimobendan 2
Lotilaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Photophobia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (90 here).

Similar death-coded share

Nearest other reactions by death-coded share (7.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Photophobia (#1444 of 2,481 by report volume); death-coded 7.8%. PlainBreed reaction plate · death-coded report count stamp 7 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →