Panting

Verify with FDA CVM →

VeDDRA Code: 855

14,520 adverse event reports referencing this reaction

14,520
Total Reports
1,502
Deaths
1030.0%
Death Rate

Species Most Affected

Dog 11,762
Cat 2,717
Cattle 24
Horse 6
Goat 2
Unknown 2
Sheep 2
Other 2
Other Canids 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 1,463
Domestic Shorthair 1,382
Crossbred Canine/dog 832
Retriever - Golden 586
Shepherd Dog - German 507
Domestic Longhair 489
Dog (unknown) 347
Chihuahua 344
Shih Tzu 334
Boxer (German Boxer) 314

Associated Drugs

Nitenpyram 2,051
Afoxolaner 1,266
Milbemycin Oxime + Spinosad 1,190
Moxidectin 866
Bedinvetmab 803
Trilostane 792
Carprofen 704
Ivermectin + Pyrantel As Pamoate Salt 524
Gabapentin 474
Maropitant Citrate 464
Spinosad 460
Oclacitinib Maleate 453
Prednisone 432
Melarsomine Dihydrochloride 414
Fluralaner Chew Tablets 386
Pyrantel Pamoate;Sarolaner 378
Melarsomine Dihydrochloride Injection 312
Imidacloprid + Moxidectin 308
Sarolaner 295
Milbemycin Oxime + Praziquantel 267

Data Summary

Metric Value
Total reports referencing reaction 14,520
Reports with fatal outcome 1,502
Case-fatality rate (reported events) 1030.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 855.

Panting Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 14,520 adverse event reports that reference Panting as a reaction term, including 1,502 reports with a death outcome — a 1030.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 855, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Panting appears most frequently in reports for Dog (11,762 reports), Cat (2,717 reports), Cattle (24 reports) — with Dog dominating at 11,762 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (1,463), Domestic Shorthair (1,382), Crossbred Canine/dog (832). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Panting are Nitenpyram (2,051 reports), Afoxolaner (1,266 reports), Milbemycin Oxime + Spinosad (1,190 reports), Moxidectin (866 reports), with Nitenpyram appearing alongside this reaction in 2,051 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial