Reaction profile

The FDA adverse-event record for panting

14,520 FDA adverse-event reports reference panting (VeDDRA 855). See the species, breeds, and drugs most associated with it below.

14,520
reports citing this reaction
10.3%
death-coded share
Dog
most-affected species
Nitenpyram
most-associated drug
Verify with FDA CVM →
14,520
Total Reports
1,502
Deaths
10.3%
Death Rate

Species Most Affected

Dog 11,762
Cat 2,717
Cattle 24
Horse 6
Goat 2
Unknown 2
Sheep 2
Other 2
Other Canids 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 1,463
Domestic Shorthair 1,382
Crossbred Canine/dog 832
Retriever - Golden 586
Shepherd Dog - German 507
Domestic Longhair 489
Dog (unknown) 347
Chihuahua 344
Shih Tzu 334
Boxer (German Boxer) 314

Associated Drugs

Nitenpyram 2,051
Afoxolaner 1,266
Milbemycin Oxime + Spinosad 1,190
Moxidectin 866
Bedinvetmab 803
Trilostane 792
Carprofen 704
Ivermectin + Pyrantel As Pamoate Salt 524
Gabapentin 474
Maropitant Citrate 464
Spinosad 460
Oclacitinib Maleate 453
Prednisone 432
Melarsomine Dihydrochloride 414
Fluralaner Chew Tablets 386
Pyrantel Pamoate;Sarolaner 378
Melarsomine Dihydrochloride Injection 312
Imidacloprid + Moxidectin 308
Sarolaner 295
Milbemycin Oxime + Praziquantel 267

Panting Reaction Insights

14,520 reports name Panting; 1,502 recorded a death outcome (10.3% of reported events, not a population-level mortality rate). VeDDRA code: 855.

By species: Dog (11,762 reports), Cat (2,717 reports), Cattle (24 reports). By breed: Retriever - Labrador (1,463), Domestic Shorthair (1,382), Crossbred Canine/dog (832).

Most co-reported drugs: Nitenpyram (2,051 reports), Afoxolaner (1,266 reports), Milbemycin Oxime + Spinosad (1,190 reports), Moxidectin (866 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.