Reaction profile

The FDA adverse-event record for thickened ear canal(s)

31 FDA reports name thickened ear canal(s), a lower-volume reaction in the CVM extract (VeDDRA 2456). Plate stamps and neighbourhood peers follow.

#1986 of 2,481
by report volume (all reactions)
31
reports citing this reaction
6.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Thickened ear canal(s) has 31 reports now versus 29 in that prior snapshot: 2 more (6.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Thickened ear canal(s) changes

FDA AER · VeDDRA plate

Code 2456 VOL-TRACE

VOL-TRACE · DEATH-PAR · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 31 reports
  • DEATH-PAR 6.5%
  • LOWER-Q #1986/2481
  • PHOTO-FINISH ABNORMAL TEST RESULT,…
  • SPECIES-DOG Dog · 25
  • DRUG-LEAD Prednisone · 9
  • DESK-WIDE 16 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Thickened ear canal

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL TEST RESULT,… · near31ALBUMIN HIGH, URINE · near31BILE ACIDS ABNORMAL,… · near31Clonic seizure · near31Thickened ear canal(s) · thi…31Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Thickened ear canal(s)

Thickened ear canal(s): low death-coded share in the FDA AER plate

Signature read: 2 death-coded reports is a thin tail count for Thickened ear canal(s) in the CVM extract. Report volume is lower-third scale: 31 named reports in the openFDA extract. Death-coded share is lower-third: 2 of 31 reports (6.5% of named reports). Nearest volume peer: ABNORMAL TEST RESULT, THYROID NOS (±0 reports). Lead species Dog (25). Lead co-reported drug Prednisone (9).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Prednisone appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 25
Cat 6

Breeds Most Affected

Retriever - Labrador 6
Retriever - Golden 4
Domestic Longhair 4
Beagle 2
Bulldog 2
Domestic Shorthair 2
Terrier - Rat 2
Crossbred Canine/dog 1
Shih Tzu 1
Griffon - French Wire-haired Pointing 1

Associated Drugs

Prednisone 9
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 6
Oclacitinib Maleate 4
Diphenhydramine 4
Maropitant Citrate 4
Selamectin 4
Enrofloxacin 3
Ear Cleaner (Unknown) 3
Gabapentin 3
Thiabendazole + Dexamethasone + Neomycin 3
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 3
Betamethasone + Florfenicol + Terbinafine 2
Afoxolaner 2
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 2
Omeprazole 2
Tramadol 2
Trilostane 2
Cephalexin 2
Cyclosporine 2
Thiamazole 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thickened ear canal(s) (#1986 of 2,481 by report volume); death-coded 6.5%. PlainBreed reaction plate · death-coded report count stamp 2 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →