Reaction profile

The FDA adverse-event record for vaginal haemorrhage

136 FDA adverse-event reports reference vaginal haemorrhage (VeDDRA 817). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1237 of 2,481
by report volume (all reactions)
136
reports citing this reaction
14.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vaginal haemorrhage has 136 reports now versus 134 in that prior snapshot: 2 more (1.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vaginal haemorrhage changes

FDA AER · VeDDRA plate

Code 817 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 136 reports
  • DEATH-ELEV 14.7%
  • MID-PACK #1237/2481
  • PHOTO-FINISH Tracheal and laryngea…
  • SPECIES-DOG Dog · 116
  • DRUG-LEAD Estriol Tablets · 57
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tracheal and laryngeal disorder NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Vaginal haemorrhage

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Tracheal and laryngea… · near136Vaginal haemorrhage · this r…136Abnormal serum protei… · near135Cholangiohepatitis · near135Decreased mean corpus… · near135Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vaginal haemorrhage

What the FDA AER plate says about Vaginal haemorrhage

Signature read: 20 death-coded reports is the most distinctive absolute-outcome stamp on Vaginal haemorrhage. Report volume sits in the middle third of the reaction corpus. 20 of 136 reports were death-coded (14.7% of named reports, not a population mortality rate). Nearest volume peer: Tracheal and laryngeal disorder NOS (±0 reports). Lead species Dog (116). Lead co-reported drug Estriol Tablets (57).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Estriol Tablets appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 116
Human 8
Cat 5
Other 2
Cattle 2
Horse 1
Goat 1
Hamster 1

Breeds Most Affected

Crossbred Canine/dog 20
Unknown 10
Retriever - Labrador 10
Doberman Pinscher 7
Beagle 6
Chihuahua 5
Pug 4
Poodle - Toy 3
Spaniel - King Charles Cavalier 3
Domestic (unspecified) 2

Associated Drugs

Estriol Tablets 57
Estriol 10
Carprofen 9
Bedinvetmab 7
Milbemycin Oxime + Spinosad 5
Fluralaner Chew Tablets 5
Gabapentin 5
Oclacitinib Maleate 4
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 4
Progesterone 3
Maropitant Citrate 3
Famotidine 3
Enrofloxacin 3
Milbemycin Oxime + Praziquantel 3
Selamectin 2
Altrenogest 2
Melarsomine Dihydrochloride 2
Dinoprost Tromethamine 2
Spinosad 2
Firocoxib 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Vaginal haemorrhage, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (14.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vaginal haemorrhage (#1237 of 2,481 by report volume); death-coded 14.7%. PlainBreed reaction plate · death-coded report count stamp 20 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →