Reaction profile

The FDA adverse-event record for skin vascular disorder nos

48 FDA reports name skin vascular disorder nos, a lower-volume reaction in the CVM extract (VeDDRA 973). Plate stamps and neighbourhood peers follow.

#1764 of 2,481
by report volume (all reactions)
48
reports citing this reaction
10.4%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Skin vascular disorder NOS has 48 reports now versus 48 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Skin vascular disorder NOS changes

FDA AER · VeDDRA plate

Code 973 VOL-TRACE

VOL-TRACE · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 48 reports
  • DEATH-ELEV 10.4%
  • MID-PACK #1764/2481
  • PHOTO-FINISH Abnormal echocardiogr…
  • SPECIES-DOG Dog · 43
  • DRUG-LEAD Trilostane · 7
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal echocardiogram (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Skin vascular disorder NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal echocardiogr… · near48Application site absc… · near48Brain damage NOS · near48Brain tumour · near48Skin vascular disorde… · thi…48Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Skin vascular disorder NOS

What the FDA AER plate says about Skin vascular disorder NOS

Signature read: 5 death-coded reports is a thin tail count for Skin vascular disorder NOS in the CVM extract. Report volume is lower-third scale: 48 named reports in the openFDA extract. 5 of 48 reports were death-coded (10.4% of named reports, not a population mortality rate). Nearest volume peer: Abnormal echocardiogram (±0 reports). Lead species Dog (43). Lead co-reported drug Trilostane (7).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 43
Cat 4
Horse 1

Breeds Most Affected

Shih Tzu 5
Chihuahua 5
Retriever - Labrador 4
Domestic Shorthair 3
Dachshund - Miniature 2
Terrier - Yorkshire 2
Retriever - Golden 2
Weimaraner 1
Dalmatian 1
Pug 1

Associated Drugs

Trilostane 7
Moxidectin 5
Prednisone 5
Milbemycin Oxime + Spinosad 4
Carprofen 4
Cefpodoxime Proxetil 3
Hydroxyzine 3
Maropitant Citrate 3
Oclacitinib Maleate 3
Cefovecin 3
Rabies Vaccine, Killed Virus 3
Spinosad 2
Cyclosporine A 2
Diphenhydramine Hcl 2
Gabapentin 2
Afoxolaner 2
Nitenpyram 2
Marbofloxacin 2
Meloxicam 2
Verdinexor 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Skin vascular disorder NOS (#1764 of 2,481 by report volume); death-coded 10.4%. PlainBreed reaction plate · death-coded report count stamp 5 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →