Reaction profile

The FDA adverse-event record for dehydration

7,301 FDA adverse-event reports reference dehydration (VeDDRA 1208). See the species, breeds, and drugs most associated with it below.

7,301
reports citing this reaction
26.5%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
7,301
Total Reports
1,935
Deaths
26.5%
Death Rate

Species Most Affected

Dog 5,024
Cat 2,092
Horse 76
Cattle 37
Chicken 17
Human 16
Turkey 11
Pig 4
Ferret 3
Sheep 2

Breeds Most Affected

Domestic Shorthair 1,259
Retriever - Labrador 556
Crossbred Canine/dog 372
Chihuahua 275
Terrier - Yorkshire 231
Retriever - Golden 198
Domestic (unspecified) 192
Shih Tzu 176
Dachshund (unspecified) 141
Domestic Longhair 140

Associated Drugs

Maropitant Citrate 731
Milbemycin Oxime + Spinosad 653
Carprofen 604
Spinosad 348
Meloxicam 336
Cefovecin 322
Moxidectin 297
Deracoxib 259
Buprenorphine 259
Gabapentin 259
Trilostane 233
Afoxolaner 224
Fluralaner Chew Tablets 224
Selamectin 205
Famotidine 202
Bexagliflozin 202
Pyrantel Pamoate;Sarolaner 186
Prednisone 181
Metronidazole 168
Oclacitinib Maleate 167

Dehydration Reaction Insights

7,301 reports name Dehydration; 1,935 recorded a death outcome (26.5% of reported events, not a population-level mortality rate). VeDDRA code: 1208.

By species: Dog (5,024 reports), Cat (2,092 reports), Horse (76 reports). By breed: Domestic Shorthair (1,259), Retriever - Labrador (556), Crossbred Canine/dog (372).

Most co-reported drugs: Maropitant Citrate (731 reports), Milbemycin Oxime + Spinosad (653 reports), Carprofen (604 reports), Spinosad (348 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.