Reaction profile

The FDA adverse-event record for lack of efficacy (virus) - herpesvirus nos

11 FDA reports name lack of efficacy (virus) - herpesvirus nos, a lower-volume reaction in the CVM extract (VeDDRA 2820). Plate stamps and neighbourhood peers follow.

#2428 of 2,481
by report volume (all reactions)
11
reports citing this reaction
63.6%
death-coded share
Cattle
most-affected species

FDA AER · VeDDRA plate

Code 2820 VOL-TRACE

VOL-TRACE · DEATH-HOT · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-MID · BOOK-FULL

  • VOL-TRACE 11 reports
  • DEATH-HOT 63.6%
  • BOTTOM-DECILE #2428/2481
  • PHOTO-FINISH ABNORMAL PANCREATIC S…
  • SPECIES-CATTLE Cattle · 7
  • DRUG-LEAD Feline Caliciviru… · 3
  • DESK-MID 7 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lack of efficacy - herpesvirus NOS

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ABNORMAL PANCREATIC S… · near11Aortic stenosis · near11Aqueous flare · near11Bile duct inflammation · near11Lack of efficacy (vir… · thi…11Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (virus) - herpesvirus NOS

Lack of efficacy (virus) - herpesvirus NOS: high death-coded share in the FDA AER plate

Signature read: 11 reports place Lack of efficacy (virus) - herpesvirus NOS in the lower third of FDA AER volume (#2428 of 2,481). Report volume is lower-third scale: 11 named reports in the openFDA extract. Death-coded share is upper-third: 7 of 11 reports (63.6% of named reports). Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports). Lead species Cattle (7). Lead co-reported drug Feline Calicivirus, Strain F-9, Passage 7, Lot A;Feline Viral Rhinotracheitis, S (3).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 7
Cat 3
Horse 1

Breeds Most Affected

Domestic Shorthair 3
Mixed (Cattle) 3
Quarter Horse 1
Cattle (unknown) 1
Aberdeen Angus 1
Holstein-Friesian also known as Holstein 1
Crossbred Bovine/Cattle 1

Associated Drugs

Feline Calicivirus, Strain F-9, Passage 7, Lot A;Feline Viral Rhinotracheitis, S 3
Bovine Parainfluenza 3, Pi3 Ebk-1/Ebht-1 Strain Al-Im;Bovine Respiratory Syncyti 3
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea Type 1, Modified Live Virus + Bovine Virus Diarrhea Type 2, Modified Live Virus + Mannheimia Haemolytica Toxoid 2
Tulathromycin 2
Amoxicillin Trihydrate 1
Pergolide Mesylate 1
Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus 1
Eastern Encephalomyelitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus 1
Eprinomectin 1
Bovine Parainfluenza 3 Virus, Modified Live Virus + Bovine Respiratory Syncytial Virus, Modified Live Virus + Bovine Rhinotracheitis Virus, Modified Live Virus + Bovine Virus Diarrhea, Modified Live Virus + Leptospira Canicola Bacterin + Leptospira Grippotyphosa Bacterin + Leptospira Hardjo Bacterin + Leptospira Icterohaemorrhagiae Bacterin + Leptospira Pomona Bacterin 1
Clostridium Chauvoei + Clostridium Novyi + Clostridium Perfringens Type C + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum + Clostridium Sordellii 1
Mannheimia Haemolytica Toxoid 1
Clostridium Chauvoei Bacterin Toxoid + Clostridium Novyi Bacterin Toxoid + Clostridium Perfringens Type C Bacterin Toxoid + Clostridium Perfringens Type D Bacterin Toxoid + Clostridium Septicum Bacterin Toxoid + Clostridium Sordellii Bacterin Toxoid + Moraxella Bovis Bacterin Toxoid 1
Ibr/Brsv/Pi3/Bvd Lv+Vib/Lep*5 1
Fenbendazol Suspension 1
Cloprostenol 263 Inj Cattle 1
Gonadorelin Injectable 1
Lambda-Cyhalotrin/Pip But P-On 1
Bovine Virus*5/Past M+Mh Lv/Lb 1
Clostr Perf*2/Clos Others*4 Kb 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (virus) - herpesvirus NOS (#2428 of 2,481 by report volume); death-coded 63.6%. PlainBreed reaction plate · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →