Reaction profile

The FDA adverse-event record for horizontal nystagmus

502 FDA adverse-event reports reference horizontal nystagmus (VeDDRA 1143). See the species, breeds, and drugs most associated with it below.

502
reports citing this reaction
14.7%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
502
Total Reports
74
Deaths
14.7%
Death Rate

Species Most Affected

Dog 361
Cat 130
Horse 7
Rabbit 2
Cattle 1
Other Equids 1

Breeds Most Affected

Domestic Shorthair 65
Crossbred Canine/dog 26
Retriever - Labrador 25
Domestic (unspecified) 20
Bulldog - French 19
Retriever - Golden 19
Shih Tzu 14
Collie - Border 14
Chihuahua 13
Shepherd Dog - Australian 12

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 80
Bedinvetmab 65
Maropitant Citrate 40
Afoxolaner 26
Carprofen 23
Gabapentin 22
Milbemycin Oxime + Spinosad 18
Cefovecin 17
Fluralaner Chew Tablets 17
Fluralaner 13.64% 12-Week Chew 16
Enrofloxacin 14
Pyrantel Pamoate;Sarolaner 14
Selamectin 13
Prednisone 13
Butorphanol 13
Dexmedetomidine Hydrochloride 12
Rabies Vaccine 12
Ivermectin + Pyrantel As Pamoate Salt 12
Spinosad 11
Ear Cleaner (Unknown) 11

Horizontal nystagmus Reaction Insights

502 reports name Horizontal nystagmus; 74 recorded a death outcome (14.7% of reported events, not a population-level mortality rate). VeDDRA code: 1143.

By species: Dog (361 reports), Cat (130 reports), Horse (7 reports). By breed: Domestic Shorthair (65), Crossbred Canine/dog (26), Retriever - Labrador (25).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (80 reports), Bedinvetmab (65 reports), Maropitant Citrate (40 reports), Afoxolaner (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.