Reaction profile

The FDA adverse-event record for horizontal nystagmus

553 FDA reports name horizontal nystagmus, a high-volume reaction in the CVM extract (VeDDRA 1143). Plate stamps and neighbourhood peers follow.

#603 of 2,481
by report volume (all reactions)
553
reports citing this reaction
15.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Horizontal nystagmus has 553 reports now versus 526 in that prior snapshot: 27 more (5.1%).

Report change
+27
Death-coded reports
+6
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Horizontal nystagmus changes

FDA AER · VeDDRA plate

Code 1143 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 553 reports
  • DEATH-ELEV 15.6%
  • UPPER-Q #603/2481
  • PHOTO-FINISH Gastric ulcer
  • SPECIES-DOG Dog · 404
  • DRUG-LEAD Bedinvetmab · 90
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Gastric ulcer (±2 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Horizontal nystagmus

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Horizontal nystagmus · this …553Gastric ulcer · near551Sleep disturbance NOS · near551Fly biting behaviour · near550Increased borborygmus · near550Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Horizontal nystagmus

What the FDA AER plate says about Horizontal nystagmus

Signature read: 86 death-coded reports is a heavy tail count for Horizontal nystagmus in the CVM extract. Report volume is upper-third scale: 553 named reports in the openFDA extract. 86 of 553 reports were death-coded (15.6% of named reports, not a population mortality rate). Nearest volume peer: Gastric ulcer (±2 reports). Lead species Dog (404). Lead co-reported drug Bedinvetmab (90).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 404
Cat 138
Horse 7
Rabbit 2
Cattle 1
Other Equids 1

Breeds Most Affected

Domestic Shorthair 69
Retriever - Labrador 35
Crossbred Canine/dog 29
Bulldog - French 22
Retriever - Golden 22
Domestic (unspecified) 20
Shih Tzu 15
Collie - Border 15
Chihuahua 14
Shepherd Dog - Australian 13

Associated Drugs

Bedinvetmab 90
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 86
Maropitant Citrate 48
Carprofen 34
Gabapentin 30
Afoxolaner 29
Pyrantel Pamoate;Sarolaner 20
Milbemycin Oxime + Spinosad 18
Cefovecin 17
Fluralaner Chew Tablets 17
Fluralaner 13.64% 12-Week Chew 17
Enrofloxacin 16
Butorphanol 15
Rabies Vaccine 14
Selamectin 13
Prednisone 13
Grapiprant 13
Alfaxalone 13
Dexmedetomidine Hydrochloride 12
Ivermectin + Pyrantel As Pamoate Salt 12

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Horizontal nystagmus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (553 here).

Similar death-coded share

Nearest other reactions by death-coded share (15.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Horizontal nystagmus (#603 of 2,481 by report volume); death-coded 15.6%. PlainBreed reaction plate · death-coded report count stamp 86 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →