Reaction profile

The FDA adverse-event record for optic disc oedema

10 FDA adverse-event reports reference optic disc oedema (VeDDRA 2237). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
20.0%
death-coded share
Dog
most-affected species
Fluralaner Chew Tablets
most-associated drug
Verify with FDA CVM →
10
Total Reports
2
Deaths
20.0%
Death Rate

Species Most Affected

Dog 8
Cat 2

Breeds Most Affected

Domestic Shorthair 2
Bulldog 1
Terrier - Rat 1
Crossbred Canine/dog 1
Collie - Border 1
Bulldog - American 1
Shih Tzu 1
Dog (unknown) 1
Ridgeback - Rhodesian 1

Associated Drugs

Fluralaner Chew Tablets 4
Carprofen 1
Vitamins 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Afoxolaner 68 Mg Chewable Tablets 1
Milbemycin Oxime + Spinosad 1
Spinosad 1
Oclacitinib 1
Enrofloxacin + Silver Sulfadiazine 1
Prednisolone 1
Doxycycline 1
Ocular Lubricant 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Acetic Acid/Boric Acid Ear Cleaner 1
Distemper Combination Vaccine 1
Rabies 1
Lyme Vaccine 1
Prednisone 1
Frunevetmab 1

Optic disc oedema Reaction Insights

10 reports name Optic disc oedema; 2 recorded a death outcome (20.0% of reported events, not a population-level mortality rate). VeDDRA code: 2237.

By species: Dog (8 reports), Cat (2 reports). By breed: Domestic Shorthair (2), Bulldog (1), Terrier - Rat (1).

Most co-reported drugs: Fluralaner Chew Tablets (4 reports), Carprofen (1 reports), Vitamins (1 reports), Afoxolaner (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.