Stridor (Upper respiratory; for lower respiratory see also Bronchial rale)

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VeDDRA Code: 1953

160 adverse event reports referencing this reaction

160
Total Reports
39
Deaths
2440.0%
Death Rate

Species Most Affected

Dog 113
Cat 32
Horse 13
Cattle 2

Breeds Most Affected

Retriever - Labrador 15
Domestic Shorthair 14
Pug 11
Bulldog 7
Retriever - Golden 6
Chihuahua 6
Quarter Horse 5
Crossbred Canine/dog 5
Domestic Longhair 4
Terrier - Yorkshire 4

Associated Drugs

Maropitant Citrate 18
Moxidectin 17
Bedinvetmab 16
Oclacitinib Maleate 10
Afoxolaner 9
Milbemycin Oxime + Spinosad 8
Cefovecin 8
Buprenorphine 7
Prednisone 7
Carprofen 7
Dexamethasone 7
Enrofloxacin 7
Gabapentin 7
Detomidine Hydrochloride 6
Trilostane 6
Frunevetmab 6
Diphenhydramine Hcl 5
Tramadol 5
Pimobendan 4
Fluralaner Chew Tablets 4

Data Summary

Metric Value
Total reports referencing reaction 160
Reports with fatal outcome 39
Case-fatality rate (reported events) 2440.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1953.

Stridor (Upper respiratory; for lower respiratory see also Bronchial rale) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 160 adverse event reports that reference Stridor (Upper respiratory; for lower respiratory see also Bronchial rale) as a reaction term, including 39 reports with a death outcome — a 2440.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1953, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Stridor (Upper respiratory; for lower respiratory see also Bronchial rale) appears most frequently in reports for Dog (113 reports), Cat (32 reports), Horse (13 reports) — with Dog dominating at 113 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (15), Domestic Shorthair (14), Pug (11). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Stridor (Upper respiratory; for lower respiratory see also Bronchial rale) are Maropitant Citrate (18 reports), Moxidectin (17 reports), Bedinvetmab (16 reports), Oclacitinib Maleate (10 reports), with Maropitant Citrate appearing alongside this reaction in 18 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial