Reaction profile

The FDA adverse-event record for head shake - behavioural disorder

1,152 FDA reports name head shake - behavioural disorder, a high-volume reaction in the CVM extract (VeDDRA 2412). Plate stamps and neighbourhood peers follow.

#349 of 2,481
by report volume (all reactions)
1,152
reports citing this reaction
4.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Head shake - behavioural disorder has 1,152 reports now versus 1,134 in that prior snapshot: 18 more (1.6%).

Report change
+18
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Head shake - behavioural disorder changes

FDA AER · VeDDRA plate

Code 2412 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,152 reports
  • DEATH-LOW 4.0%
  • UPPER-Q #349/2481
  • PHOTO-FINISH Head tilt - neurologi…
  • SPECIES-DOG Dog · 779
  • DRUG-LEAD Imidacloprid + Mo… · 104
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Head tilt - neurological disorder (see also Head tilt - ear disorder) (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Head shake - behavioural disorder

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Allergy NOS · near1155Head tilt - neurologi… · near1153Head shake - behaviou… · thi…1152Excessive thirst · near1144Cardiac enlargement · near1140Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Head shake - behavioural disorder

Head shake - behavioural disorder: low death-coded share in the FDA AER plate

Signature read: 1,152 reports place Head shake - behavioural disorder in the upper third of FDA AER volume (#349 of 2,481). Report volume is upper-third scale: 1,152 named reports in the openFDA extract. Death-coded share is lower-third: 46 of 1,152 reports (4.0% of named reports). Nearest volume peer: Head tilt - neurological disorder (see also Head tilt - ear disorder) (±1 reports). Lead species Dog (779). Lead co-reported drug Imidacloprid + Moxidectin (104).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Imidacloprid + Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 779
Cat 311
Horse 49
Cattle 10
Donkey 2
Alpaca 1

Breeds Most Affected

Domestic Shorthair 178
Retriever - Labrador 100
Crossbred Canine/dog 56
Dog (unknown) 55
Retriever - Golden 46
Cat (unknown) 43
Terrier - Yorkshire 34
Chihuahua 32
Shih Tzu 26
Domestic Mediumhair 24

Associated Drugs

Imidacloprid + Moxidectin 104
Afoxolaner 103
Pyrantel Pamoate;Sarolaner 76
Moxidectin 73
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 58
Fluralaner Spot-On Solution 54
Fluralaner Chew Tablets 53
Sarolaner 44
Milbemycin Oxime + Spinosad 38
Fluralaner 13.64% 12-Week Chew 37
Lotilaner 34
Ivermectin + Pyrantel As Pamoate Salt 32
Milbemycin Oxime + Praziquantel 29
Nitenpyram 28
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 27
Eprinomectin + Esafoxolaner + Praziquantel 27
Bedinvetmab 24
Oclacitinib Maleate 23
Prednisone 22
Capromorelin Tartrate 22

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Head shake - behavioural disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Head shake - behavioural disorder (#349 of 2,481 by report volume); death-coded 4.0%. PlainBreed reaction plate · report volume stamp 1,152 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →