Reaction profile

The FDA adverse-event record for convulsive disorder nos

31 FDA adverse-event reports reference convulsive disorder nos (VeDDRA 1397). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
31
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 29
Horse 1
Cat 1

Breeds Most Affected

Spaniel - Cocker American 3
Retriever - Labrador 2
Shepherd (unspecified) 2
Shih Tzu 2
Shepherd Dog - German 2
Chihuahua 2
Maltese 2
Terrier - Yorkshire 2
Retriever (unspecified) 1
Deutsche Dogge, Great Dane 1

Associated Drugs

Milbemycin Oxime + Spinosad 8
Ivermectin + Pyrantel As Pamoate Salt 5
Afoxolaner 4
Ivermectin 2
Afoxolaner 68 Mg Chewable Tablets 2
Sarolaner 2
Fluralaner Spot-On Solution 2
Fluralaner 13.64% 12-Week Chew 2
Ofloxacin 2
Meloxicam 2
Amoxicillin + Clavulanic Acid 2
Gabapentin 2
Fluoxetine Hydrochloride 1
Alprazolam 1
Monensin Sodium 1
Spinosad 1
Milbemcyin Oxime, Lufenuron, Praziquantel 1
Milbemycin Oxime, Lufenuron 1
Milbemycin + Spinosad 1
Propofol 1

Convulsive disorder NOS Reaction Insights

31 reports name Convulsive disorder NOS; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 1397.

By species: Dog (29 reports), Horse (1 reports), Cat (1 reports). By breed: Spaniel - Cocker American (3), Retriever - Labrador (2), Shepherd (unspecified) (2).

Most co-reported drugs: Milbemycin Oxime + Spinosad (8 reports), Ivermectin + Pyrantel As Pamoate Salt (5 reports), Afoxolaner (4 reports), Ivermectin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.