Reaction profile

The FDA adverse-event record for swollen lymph node

404 FDA reports name swollen lymph node, a high-volume reaction in the CVM extract (VeDDRA 1818). Plate stamps and neighbourhood peers follow.

#723 of 2,481
by report volume (all reactions)
404
reports citing this reaction
22.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Swollen lymph node has 404 reports now versus 399 in that prior snapshot: 5 more (1.3%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Swollen lymph node changes

FDA AER · VeDDRA plate

Code 1818 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 404 reports
  • DEATH-HOT 22.8%
  • MID-PACK #723/2481
  • PHOTO-FINISH Focal seizure
  • SPECIES-DOG Dog · 353
  • DRUG-LEAD Oclacitinib Malea… · 60
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Focal seizure (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Swollen lymph node

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Loss of vision · near405Oral ulceration · near405Focal seizure · near404Swollen lymph node · this re…404Drooping eyelid · near402Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Swollen lymph node

What the FDA AER plate says about Swollen lymph node

Signature read: 92 death-coded reports is a heavy tail count for Swollen lymph node in the CVM extract. Report volume is upper-third scale: 404 named reports in the openFDA extract. 92 of 404 reports were death-coded (22.8% of named reports, not a population mortality rate). Nearest volume peer: Focal seizure (±0 reports). Lead species Dog (353). Lead co-reported drug Oclacitinib Maleate (60).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 353
Cat 41
Human 3
Cattle 3
Horse 3
Pig 1

Breeds Most Affected

Retriever - Labrador 35
Domestic Shorthair 29
Crossbred Canine/dog 23
Retriever - Golden 21
Chihuahua 14
Dog (unknown) 14
Boxer (German Boxer) 11
Collie - Border 10
Shepherd Dog - German 10
Terrier - Bull - American Pit 10

Associated Drugs

Oclacitinib Maleate 60
Milbemycin Oxime + Spinosad 42
Carprofen 40
Maropitant Citrate 28
Afoxolaner 28
Cyclosporine 16
Prednisone 15
Gabapentin 15
Ivermectin + Pyrantel As Pamoate Salt 15
Tigilanol Tiglate 15
Bedinvetmab 15
Spinosad 14
Trilostane 13
Cefovecin 13
Cyclosporine A 12
Meloxicam 10
Metronidazole 10
Moxidectin 10
Imidacloprid + Moxidectin 8
Ivermectin 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Swollen lymph node, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (404 here).

Similar death-coded share

Nearest other reactions by death-coded share (22.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Swollen lymph node (#723 of 2,481 by report volume); death-coded 22.8%. PlainBreed reaction plate · death-coded report count stamp 92 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →