Reaction profile

The FDA adverse-event record for erythematous rash

422 FDA adverse-event reports reference erythematous rash (VeDDRA 1449). See the species, breeds, and drugs most associated with it below.

422
reports citing this reaction
2.6%
death-coded share
Dog
most-affected species
Fluralaner Chew Tablets
most-associated drug
Verify with FDA CVM →
422
Total Reports
11
Deaths
2.6%
Death Rate

Species Most Affected

Dog 363
Cat 32
Human 26
Horse 1

Breeds Most Affected

Retriever - Labrador 34
Chihuahua 33
Crossbred Canine/dog 28
Unknown 27
Pit Bull 21
Domestic Shorthair 21
Shih Tzu 16
Retriever - Golden 15
Terrier - Yorkshire 14
Shepherd Dog - German 13

Associated Drugs

Fluralaner Chew Tablets 49
Milbemycin Oxime + Spinosad 36
Afoxolaner 26
Moxidectin 23
Oclacitinib Maleate 22
Imidacloprid + Moxidectin 19
Selamectin 19
Bedinvetmab 19
Spinosad 15
Cefovecin 14
Nitenpyram 14
Gabapentin 13
Prednisone 12
Maropitant Citrate 12
Diphenhydramine 12
Anti-Il31 Mab Mcs Lot #1283563 12
Pyrantel Pamoate;Sarolaner 12
Milbemycin Oxime + Praziquantel 11
Sarolaner 11
Afoxolaner 28.3 Mg Chewable Tablets 10

Erythematous rash Reaction Insights

422 reports name Erythematous rash; 11 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). VeDDRA code: 1449.

By species: Dog (363 reports), Cat (32 reports), Human (26 reports). By breed: Retriever - Labrador (34), Chihuahua (33), Crossbred Canine/dog (28).

Most co-reported drugs: Fluralaner Chew Tablets (49 reports), Milbemycin Oxime + Spinosad (36 reports), Afoxolaner (26 reports), Moxidectin (23 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.