Other coagulation abnormality NOS

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VeDDRA Code: 152

136 adverse event reports referencing this reaction

136
Total Reports
52
Deaths
3820.0%
Death Rate

Species Most Affected

Dog 114
Cat 18
Horse 3
Pig 1

Breeds Most Affected

Retriever - Labrador 26
Domestic Shorthair 9
Shepherd Dog - German 6
Retriever - Golden 5
Dachshund (unspecified) 4
Beagle 4
Crossbred Canine/dog 4
Shepherd Dog - Australian 4
Maltese 3
Terrier - Yorkshire 3

Associated Drugs

Carprofen 37
Maropitant Citrate 24
Milbemycin Oxime + Spinosad 21
Famotidine 12
Moxidectin 10
Sucralfate 10
Ampicillin 10
Propofol 9
Isoflurane 9
Buprenorphine 9
Meloxicam 9
Vitamin K1 8
Sam-E, Silybin, Vitamin E, Zinc 8
Polysulfated Glycosaminoglycan 8
Metronidazole 7
Plasma 7
Cefovecin 7
Afoxolaner 6
Amoxicillin 5
Acepromazine Maleate 5

Data Summary

Metric Value
Total reports referencing reaction 136
Reports with fatal outcome 52
Case-fatality rate (reported events) 3820.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 152.

Other coagulation abnormality NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 136 adverse event reports that reference Other coagulation abnormality NOS as a reaction term, including 52 reports with a death outcome — a 3820.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 152, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Other coagulation abnormality NOS appears most frequently in reports for Dog (114 reports), Cat (18 reports), Horse (3 reports) — with Dog dominating at 114 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (26), Domestic Shorthair (9), Shepherd Dog - German (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Other coagulation abnormality NOS are Carprofen (37 reports), Maropitant Citrate (24 reports), Milbemycin Oxime + Spinosad (21 reports), Famotidine (12 reports), with Carprofen appearing alongside this reaction in 37 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial