Reaction profile

The FDA adverse-event record for stiff knee

Name: Stiff knee - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

10 FDA reports name stiff knee, a lower-volume reaction in the CVM extract (VeDDRA 1792). Plate stamps and neighbourhood peers follow.

#2475 of 2,481
by report volume (all reactions): 10
reports citing this reaction: 10.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Stiff knee has 10 reports now versus 10 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Stiff knee changes

FDA AER · VeDDRA plate

Code 1792 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 10 reports
DEATH-ELEV 10.0%
BOTTOM-DECILE #2475/2481
PHOTO-FINISH Anoxia
SPECIES-DOG Dog · 7
DRUG-LEAD Bedinvetmab · 5
DESK-WIDE 8 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Stiff knee

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Stiff knee

What the FDA AER plate says about Stiff knee

Signature read: 10 reports place Stiff knee in the lower third of FDA AER volume (#2475 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. 1 of 10 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (7). Lead co-reported drug Bedinvetmab (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7

Human 2

Cat 1

Breeds Most Affected

Unknown 2

Retriever - Labrador 2

Domestic Shorthair 1

Terrier - Yorkshire 1

Terrier - Cairn 1

Terrier - Rat 1

Retriever - Golden 1

Retriever - Flat-coated 1

Associated Drugs

Bedinvetmab 5

Eprinomectin 5% Injection 1

Cefovecin 1

Fluralaner Chew Tablets 1

Trilostane 1

Lokivetmab 1

Dinoprost Tromethamine 1

Insulin 1

Adequan 1

Gabapentin 1

Prednisone 1

Omega 3 1

Ilunocitinib 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Stiff knee (#2475 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →