Reaction profile

The FDA adverse-event record for pr-bone marrow, lesion(s)

58 FDA adverse-event reports reference pr-bone marrow, lesion(s) (VeDDRA 99593). See the species, breeds, and drugs most associated with it below.

58
reports citing this reaction
77.6%
death-coded share
Dog
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
58
Total Reports
45
Deaths
77.6%
Death Rate

Species Most Affected

Dog 36
Cat 21
Cattle 1

Breeds Most Affected

Domestic (unspecified) 10
Domestic Shorthair 6
Crossbred Canine/dog 4
Collie - Border 4
Terrier - West Highland White 3
Retriever - Golden 3
Retriever - Labrador 3
Manx 2
Shepherd Dog - German 2
Terrier - Jack Russell 2

Associated Drugs

Cefovecin Sodium 10
Cefovecin 10
Oclacitinib Maleate 8
Carprofen 6
Doxycycline 6
Prednisone 5
Selamectin 4
Tramadol 4
Moxidectin 3
Dexamethasone 3
Famotidine 3
Buprenorphine 3
Spinosad 2
Deracoxib 2
Maropitant 2
Mirtazapine 2
Imidacolprid And Moxidectin 2
Insulin 2
Enrofloxacin 2
Ampicillin Sodium & Sulbactam Sodium 2

PR-BONE MARROW, LESION(S) Reaction Insights

58 reports name PR-BONE MARROW, LESION(S); 45 recorded a death outcome (77.6% of reported events, not a population-level mortality rate). VeDDRA code: 99593.

By species: Dog (36 reports), Cat (21 reports), Cattle (1 reports). By breed: Domestic (unspecified) (10), Domestic Shorthair (6), Crossbred Canine/dog (4).

Most co-reported drugs: Cefovecin Sodium (10 reports), Cefovecin (10 reports), Oclacitinib Maleate (8 reports), Carprofen (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.