Reaction profile

The FDA adverse-event record for pr-bone marrow, lesion(s)

58 FDA reports name pr-bone marrow, lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99593). Plate stamps and neighbourhood peers follow.

#1670 of 2,481
by report volume (all reactions)
58
reports citing this reaction
77.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-BONE MARROW, LESION(S) has 58 reports now versus 58 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-BONE MARROW, LESION(S) changes

FDA AER · VeDDRA plate

Code 99593 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 58 reports
  • DEATH-HOT 77.6%
  • MID-PACK #1670/2481
  • PHOTO-FINISH Heart block 2nd degree
  • SPECIES-DOG Dog · 36
  • DRUG-LEAD Cefovecin Sodium · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Heart block 2nd degree (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-BONE MARROW, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Heart block 2nd degree · near58Muscle degeneration · near58Ocular burn · near58Painful urination · near58PR-BONE MARROW, LESIO… · thi…58Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-BONE MARROW, LESION(S)

PR-BONE MARROW, LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-BONE MARROW, LESION(S)'s 77.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 58 named reports in the openFDA extract. Death-coded share is upper-third: 45 of 58 reports (77.6% of named reports). Nearest volume peer: Heart block 2nd degree (±0 reports). Lead species Dog (36). Lead co-reported drug Cefovecin Sodium (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 36
Cat 21
Cattle 1

Breeds Most Affected

Domestic (unspecified) 10
Domestic Shorthair 6
Crossbred Canine/dog 4
Collie - Border 4
Terrier - West Highland White 3
Retriever - Golden 3
Retriever - Labrador 3
Manx 2
Shepherd Dog - German 2
Terrier - Jack Russell 2

Associated Drugs

Cefovecin Sodium 10
Cefovecin 10
Oclacitinib Maleate 8
Carprofen 6
Doxycycline 6
Prednisone 5
Selamectin 4
Tramadol 4
Moxidectin 3
Dexamethasone 3
Famotidine 3
Buprenorphine 3
Spinosad 2
Deracoxib 2
Maropitant 2
Mirtazapine 2
Imidacolprid And Moxidectin 2
Insulin 2
Enrofloxacin 2
Ampicillin Sodium & Sulbactam Sodium 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-BONE MARROW, LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (58 here).

Similar death-coded share

Nearest other reactions by death-coded share (77.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-BONE MARROW, LESION(S) (#1670 of 2,481 by report volume); death-coded 77.6%. PlainBreed reaction plate · death-coded share stamp 77.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →