Reaction profile

The FDA adverse-event record for swollen feet

295 FDA adverse-event reports reference swollen feet (VeDDRA 1812). See the species, breeds, and drugs most associated with it below.

295
reports citing this reaction
6.4%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
295
Total Reports
19
Deaths
6.4%
Death Rate

Species Most Affected

Dog 252
Cat 38
Human 3
Cattle 2

Breeds Most Affected

Retriever - Labrador 25
Domestic Shorthair 25
Terrier - Bull - American Pit 20
Crossbred Canine/dog 19
Boxer (German Boxer) 15
Shepherd Dog - German 10
Chihuahua 9
Terrier - Yorkshire 9
Beagle 8
Bulldog - French 8

Associated Drugs

Oclacitinib Maleate 65
Moxidectin 33
Carprofen 28
Anti-Il31 Mab Mcs Lot #1283563 26
Milbemycin Oxime + Spinosad 25
Maropitant Citrate 18
Gabapentin 18
Cefovecin 17
Prednisone 14
Fluralaner Chew Tablets 12
Bedinvetmab 12
Afoxolaner 11
Selamectin 10
Buprenorphine 9
Milbemycin Oxime + Praziquantel 9
Metronidazole 8
Cyclosporine 8
Spinosad 7
Propofol 7
Antibiotic 7

Swollen feet Reaction Insights

295 reports name Swollen feet; 19 recorded a death outcome (6.4% of reported events, not a population-level mortality rate). VeDDRA code: 1812.

By species: Dog (252 reports), Cat (38 reports), Human (3 reports). By breed: Retriever - Labrador (25), Domestic Shorthair (25), Terrier - Bull - American Pit (20).

Most co-reported drugs: Oclacitinib Maleate (65 reports), Moxidectin (33 reports), Carprofen (28 reports), Anti-Il31 Mab Mcs Lot #1283563 (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.