Reaction profile

The FDA adverse-event record for tympanic discoloration

21 FDA reports name tympanic discoloration, a lower-volume reaction in the CVM extract (VeDDRA 2622). Plate stamps and neighbourhood peers follow.

#2152 of 2,481
by report volume (all reactions)
21
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Tympanic discoloration has 21 reports now versus 20 in that prior snapshot: 1 more (5.0%).

Report change
+1
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Tympanic discoloration changes

FDA AER · VeDDRA plate

Code 2622 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 21 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #2152/2481
  • PHOTO-FINISH Chewing - pruritus
  • SPECIES-DOG Dog · 13
  • DRUG-LEAD Florfenicol + Mom… · 6
  • DESK-WIDE 13 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - pruritus (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Tympanic discoloration

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Chewing - pruritus · near21Deterioration of musc… · near21External teat disorder · near21Heart disorder aggrav… · near21Tympanic discoloration · thi…21Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Tympanic discoloration

Tympanic discoloration: low death-coded share in the FDA AER plate

Signature read: Tympanic discoloration's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 21 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 21 reports (0.0% of named reports). Nearest volume peer: Chewing - pruritus (±0 reports). Lead species Dog (13). Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 13
Cat 8

Breeds Most Affected

Chihuahua 4
Domestic Shorthair 4
Domestic Longhair 2
Domestic Mediumhair 2
Terrier (unspecified) 1
Crossbred Canine/dog 1
Retriever - Labrador 1
Spaniel - King Charles Cavalier 1
Shih Tzu 1
Siberian Husky 1

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 6
Miconazole + Polymyxin B + Prednisolone 4
Genta/Momet/Clotrim Ear Oint 2
Ketoconazole 2
Lactic Acid,Salicylic Acid Otic Cleanser 2
Midazolam 2
Propofol 2
Isoflurane 2
Salicylic Acid 1
Carprofen 1
Potassium Citrate 1
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 1
Metronidazole 1
Meclizine 1
Dexamethasone + Neomycin Sulfate + Thiabendazole 1
Dexamethasone Sodium Phosphate 1
Diphenhydramine 1
Epinephrine 1
Saline 1
Selamectin;Sarolaner 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Tympanic discoloration (#2152 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →