Reaction profile

The FDA adverse-event record for lack of efficacy (lice)

450 FDA adverse-event reports reference lack of efficacy (lice) (VeDDRA 2651). See the species, breeds, and drugs most associated with it below.

450
reports citing this reaction
0.0%
death-coded share
Cattle
most-affected species
Doramectin
most-associated drug
Verify with FDA CVM →
450
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Cattle 445
Dog 3
Marsupial 1
Cat 1

Breeds Most Affected

Mixed (Cattle) 247
Cattle (other) 75
Cattle (unknown) 47
Aberdeen Angus 43
Crossbred Bovine/Cattle 7
Red Angus 6
Simmental 6
Holstein-Friesian also known as Holstein 6
Charolais 5
Dog (unknown) 2

Associated Drugs

Doramectin 279
Eprinomectin 83
Ivermectin 59
Moxidectin 14
Ivermectin 0.5% Pour-On Topical Solution 11
Breaze App Gun 80 Ml Ivomec/Eprinex 10
Portech App Gun 65 Ml Ivomec/Eprinex 3
Eprinomectin 5 Mg/Ml Pour-On Solution 2
Doramectin; Phenol 2
Permethrin-Diflubenzuron 2
Selamectin 2
Eprinomectin 5% Injection 1
Fluralaner Spot-On Solution 1
Sarolaner 1
Fenbendazol Suspension 1
Lambda-Cyhalotrin Topi Oil Sol 1
K99/Cor*2/Rota*2/Clos Per C,D 1
Permethrin 1
Unknown Pour On Insecticide 1

Lack of efficacy (lice) Reaction Insights

450 reports name Lack of efficacy (lice); 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 2651.

By species: Cattle (445 reports), Dog (3 reports), Marsupial (1 reports). By breed: Mixed (Cattle) (247), Cattle (other) (75), Cattle (unknown) (47).

Most co-reported drugs: Doramectin (279 reports), Eprinomectin (83 reports), Ivermectin (59 reports), Moxidectin (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.